No abstract

A series of 2-(trimethylstannyl)pyrroles 3, with substituents at the 3- and 4-positions, is synthesized efficiently by a base-induced reaction of stannylated TosMIC with Michael acceptors. Stille cross-couplings with bromobenzene and double cross-couplings with 1,4-dibromobenzene have been achieved successfully with the N-methyl derivative (5a) and the N-Boc derivative (6a) of 3-benzoyl-2-(trimethylstannyl)-4-phenylpyrrole (3a), despite the bulk of these stannylpyrroles. Homo-coupling reactions of the same stannylpyrroles with the corresponding bromopyrroles (prepared from stannylpyrroles 3 and NBS) were unsuccessful, probably for steric reasons.

No abstract

No abstract

Three different approaches are described for the generation of derivatives of 2,3-dimethyiene-2,3-dihydropyrrole 2, which are reactive intermediates in Diels-Alder cycloaddition reactions; one of the intramolecular cycloadditions provides a new tricyclo[3.2.1.0*~7]octane compound 8.