Objective:The aim of the present study was to evaluate the effect of low-intensity laser therapy on the wound healing process treated with steroid. Background Data: Various biological effects have been associated with low-level laser therapy (LLLT). Materials and Methods: Forty-eight rats were used, and after execution of a wound on the dorsal region of each animal, they were divided into 4 groups (n = 12), receiving the following treatments: G1 (control), wounds and animals received no treatment; G2, wounds were treated with LLLT; G3, animals received an intraperitoneal injection of steroid dosage (2 mg/kg of body weight); G4, animals received steroid and wounds were treated with LLLT. The laser emission device used was a GaAIAs (904 nm), in a contact mode, with 2.75 mW gated with 2.900 Hz during 120 sec (33 J/cm 2 ). After the period of 3, 7, and 14 days, the animals were sacrificed and the parts sent to histological processing and dyed using hematoxylin and eosin (HE) and Masson trichromium (MT) techniques. Results: The results have shown that the wounds treated with steroid had a delay in healing, while LLLT accelerated the wound healing process. Also, wounds treated with laser in the animals treated with steroid presented a differentiated healing process with a larger collagen deposition and also a decrease in both the inflamatory infiltrated and the delay on the wound healing process. Conclusion: LLLT accelerated healing, caused by the steroid, acting as a biostimulative coadjutant agent, balancing the undesirable effects of cortisone on the tissue healing process. 199

No abstract

No abstract

The aim was to study bone formation in tooth extraction sockets of rats with experimentally induced renal hypertension. As soon as hypertension was detected the upper right incisor was extracted. The animals were killed at 3, 6, 9, 12, 18 and 21 days post-extraction. At day 9 the hypertensive animals showed bone formation with little osteoblastic activity, the bone was more cellular and had immature osteoblasts and endosteal cells without trabeculae formation. In the medullary spaces oedematous connective tissue, dilated vessels and undifferentiated cells were seen. We concluded that these animals presented a different pattern of bone formation when compared to the control animals.