Diarrhea is a bowel movement or feces with liquid or semi-solid fecal water content over 200gram or 200ml / 24h (IPD Books 2014). This study aims to determine the description of Knowledge, Attitudes, and Behavior Against Mothers Who Have Toddler Diarrhea In East Jakarta Sub 2017. This research method is a descriptive survey; the population is all mothers with children in Cawang Districts samples. How sampling in this study conducted probability sampling with a simple random sampling technique. The number of samples that the researchers used was 100 respondents (people). This research was conducted on April 5, 2016. The study results found that most mothers know enough about diarrhea, that is, 41 people (41%). For the attitude of mothers and children against diarrheal disease most negative attitude is 57 people (57%). While the practice of mothers and children against diarrheal at most have a pretty good practice, which amounted to 56 (56%).