TB is considered the fourth leading cause of death. Pediatric TB is an essential factor in developing countries because the population of children aged younger than 15 years old is 40%-50% of the total population. At least 500,000 children are infected by TB annually. Globally, TB kills 200 children every single day and contributes to the death of 70,000 children annually. Immunization is one of the measures in the prevention of TB transmission. BCG vaccination has been playing the role of one of the WHO strategies since 1921 to eradicate TB problems, especially in developing countries, including Indonesia, and more than 3 billion doses of BCG vaccine have been distributed worldwide. This research aims to describe the level of mothers' knowledge regarding the BCG immunization among 0-2 months old infants in Posyandu (pre- and postnatal health care and information for women and children under five years) Kelurahan Kebun Pala Makassar, East Jakarta. The researcher used univariate analysis with the cross-sectional approach in this descriptive epidemiological research. The questionnaire that consisted of 21 questions was the primary data source for this research. The questionnaire was distributed on February 23, 2018. The researcher involved 50 respondents as the sample of the research population. Based on the analysis, the researcher concludes that 24,0% of respondents have a good level of knowledge, while the remaining respondents (76,0%) have an adequate level of expertise. Keywords: TB, BCG Immunization, Knowledge