RESUMENLa prueba molecular Genotype®MTBDRplus, es un método que permite identificar las mutaciones más frecuentes asociadas con la resistencia a las drogas antituberculosas de primera línea: isoniacida (INH) y rifampicina (RIf). El objetivo de este estudio fue evaluar el desempeño de la prueba molecular con cultivos y muestras de esputo con baciloscopía positiva. Se evaluó 95 cultivos y 100 esputos con perfiles de resistencia previamente determinados por el método de referencia "proporciones agar en placa" (APP). La prueba molecular a partir de cultivos mostró una sensibilidad de 100%; 97,5% y 96,9% para RIf, INH y multidrogorresistente (MDR) respectivamente; mientras que para esputo la sensibilidad fue de 95,7%; 96,8% y 95,2% para RIf, INH y MDR respectivamente. Se concluye que Genotype®MTBDRplus es una herramienta muy útil para la detección rápida de la resistencia a INH y RIf simultáneamente (MDR) en un máximo de 72 h a partir de esputo o de cultivo. MOLECULAR TEST GENOTYPE® MTBDRPLUS, AN ALTERNATIVE TO RAPID DETECTION OF MULTIDRUG RESISTANCE TUBERCULOSIS ABSTRACTThe Genotype®MTBDRplus molecular test is a method that allows identification of the most frequent mutations associated with resistance to major first-line antituberculosis drugs, Isoniazid (INH) and Rifampicin (RfP). The aim of this study was to evaluate the performance of the molecular test with culture and smear-positive sputum samples. We evaluated 95 cultures and 100 sputum samples with resistance profiles previously determined by the reference method "Agar Plate Proportions" (APP). The molecular test from cultures showed a sensitivity of 100 %, 97,5 % and 96,97 % for RIf, INH and MDR respectively while from sputums the sensitivity was 95,65 %, 96,77 % and 95,24 % for RIf, INH and MDR respectively. We conclude that the molecular test Genotype®MTBDRplus is a very useful tool to detect resistance to isoniazid and rifampicin simultaneously (MDR-TB) in up to 72 hours from sputum samples or cultures.

The main objective of this paper is to analyse two theoretical-methodological premises that underlie the implementation of the discussion group as a tool for qualitative analysis in social sciences research: the premises that are linked to the nature of the discourse that is generated through the application of this technique and the premises that are related to the characteristics of the method. It is concluded that it is important to reflect theoretically prior to the application of these strategies, and not to assume that they imply credibility and legitimacy in themselves.

Purpose -The purpose of this paper is to introduce the online information system Redalyc as an intermediary tool that provides Latin American scientific articles with international standards (mostly related to natural sciences and developed countries) as well as with specific areas to host local research. Design/methodology/approach -Redalyc is based on a semantic intersection model proposed by Russian semiologist Yuri Lotman. This model allows us to visualize the role played by Redalyc as a mediator between opposites, i.e. local science versus global science, and natural sciences versus social sciences. The paper presents some of the projects Redalyc has developed in conjunction with different countries and different scientific communities. Findings -The paper describes some characteristics that local projects, similar to Redalyc, must have in order to become an intermediary between scientific journal production indexes that link global parameters for scientific communication with local production. The paper finds that efforts should not only be centered on the development of strategies to change certain inertias that distinguish local social scientific production (e.g. dependence on literary resources, lack of recognition of periodical media), but also on the way they could help these disciplines and local media overcome certain barriers, namely: normalization, language and technological handicaps. Originality/value -The recognition of Latin American scientific production implies a dual process that not only involves local policies (scientific councils), but also requires producing reliable databases to provide scientists and journal editors with global references on how to produce visible scientific literature and pertinent knowledge for their contexts. Redalyc is currently a database that contributes in both ways.

Se analiza la presencia de revistas de comunicación editadas en Latinoamérica en bases de datos científicas regionales e internacionales. Se identifica su participación por país e idioma de publicación, así como su disponibilidad al público ya sea abierta o de paga. El principal hallazgo es que-pese al incremento de la profesionalización e investigación en esta área-la presencia de estas revistas en dichas bases es limitada. palabras claVe: revistas científicas de comunicación, WoS, Scopus, Acceso Abierto, comunicación científica. We analyze the existence of communication journals published in Latin America in regional and international scientific databases. We identified the country and language in which this journals are published, as well as its availability whether open access or paid. The main finding is that-despite the increase of professionalization and research in subscriptions this field-the communication journals has a limited existence in these databases.

issn impreso 0250-7161 | issn digital vol 41 | n o 123 | mayo 2015 | pp. 311-324 | tribuna | ©EURE Redes de colaboración científica en los estudios territoriales