We investigated the neural representation of locomotion in the nematode C. elegans by recording population calcium activity during movement. We report that population activity more accurately decodes locomotion than any single neuron. Relevant signals are distributed across neurons with diverse tunings to locomotion. Two largely distinct subpopulations are informative for decoding velocity and curvature, and different neurons’ activities contribute features relevant for different aspects of a behavior or different instances of a behavioral motif. To validate our measurements, we labeled neurons AVAL and AVAR and found that their activity exhibited expected transients during backward locomotion. Finally, we compared population activity during movement and immobilization. Immobilization alters the correlation structure of neural activity and its dynamics. Some neurons positively correlated with AVA during movement become negatively correlated during immobilization and vice versa. This work provides needed experimental measurements that inform and constrain ongoing efforts to understand population dynamics underlying locomotion in C. elegans.
We use the classical double copy to identify a necessary condition for a gauge theory source to constitute a single copy of a solution to Einstein's equations. In the case of four-dimensional Kerr-Schild spacetimes on Minkowski backgrounds, we extend this condition to a parameterization of the corresponding single copies. These are given by Liénard-Wiechert fields of charges on complex worldlines. This unifies the known instances of the double copy black holes on flat four-dimensional backgrounds into a single framework. Furthermore, we use the more generic condition identified to show why the black ring in five dimensions does not admit Kerr-Schild coordinates.
The presence of an active galactic nucleus (AGN) can strongly affect its host. Due to the copious radiative power of the nucleus, the effects of radiative feedback can be detected over the entire host galaxy and sometimes well into the intergalactic space. In this paper we model the observed size-luminosity relationship of the narrow-line regions (NLRs) of AGN. We model the NLR as a collection of clouds in pressure equilibrium with the ionizing radiation, with each cloud producing line emission calculated by Cloudy. The sizes of the NLRs of powerful quasars are reproduced without any free parameters, as long as they contain massive (10 5 M to 10 7 M ) ionization-bounded clouds. At lower AGN luminosities the observed sizes are larger than the model sizes, likely due to additional unmodeled sources of ionization (e.g., star formation). We find that the observed saturation of sizes at ∼ 10 kpc which is observed at high AGN luminosities (L ion 10 46 erg/s) is naturally explained by optically thick clouds absorbing the ionizing radiation and preventing illumination beyond a critical distance. Using our models in combination with observations of the [O III]/IR ratio and the [O III] size -IR luminosity relationship, we calculate the covering factor of the obscuring torus (and therefore the type 2 fraction within the quasar population) to be f = 0.5, though this is likely an upper bound. Finally, because the gas behind the ionization front is invisible in ionized gas transitions, emission-based NLR mass calculations underestimate the mass of the NLR and therefore of the energetics of ionized-gas winds.
In this work, we revisit the size-luminosity relation of the extended narrow line regions (ENLRs) using a large sample of nearby active galactic nuclei (AGN) from the Mapping Nearby Galaxies at Apache Point Observatory (MaNGA) survey. The ENLRs ionized by the AGN are identified through the spatially resolved BPT diagram, which results in a sample of 152 AGN. By combining our AGN with the literature highluminosity quasars, we found a tight log-linear relation between the size of the ENLR and the AGN [O III]λ5007Å luminosity over four orders of magnitude of the [O III] luminosity. The slope of this relation is 0.42 ± 0.02 which can be explained in terms of a distribution of clouds photoionized by the AGN. This relation also indicates the AGN have the potential to ionize and heat the gas clouds at a large distance from the nuclei without the aids of outflows and jets for the low-luminosity Seyferts. †
We record calcium activity from the majority of head neurons in freely moving C. elegans to reveal where and how natural behavior is encoded in a compact brain. We find that a sparse subset of neurons distributed throughout the head encode locomotion. A linear combination of these neurons' activity predicts the animal's velocity and body curvature and is sufficient to infer its posture. This sparse linear model outperforms single neuron or PCA models 15 at predicting behavior. Among neurons important for the prediction are well-known locomotory neurons, such as AVA, as well as neurons not traditionally associated with locomotion. We compare neural activity of the same animal during unrestrained movement and during immobilization and find large differences between brain-wide neural dynamics during real and fictive locomotion. 20One Sentence Summary: C. elegans behavior is predicted from neural activity.
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