The robustness of the reference circuit in a wide range of supply voltages is crucial in implanted devices. Conventional reference circuits have demonstrated a weak performance over wide supply ranges. Channel-length modulation in the transistors causes the circuit to be sensitive to power supply variation. To solve this inherent problem, this paper proposes a new output-voltage-line-regulation controller circuit. When a variation occurs in the power supply, the controller promptly responds to the supply deviation and removes unwanted current in the output path of the reference circuit. The proposed circuit was implemented in a 0.35-μm SK Hynix CMOS standard process. The experimental results demonstrated that the proposed reference circuit could generate a reference voltage of 0.895 V under a power supply voltage of 3.3 V, line regulation of 1.85 mV/V in the supply range of 2.3 to 5 V, maximum power supply rejection ratio (PSRR) of −54 dB, and temperature coefficient of 11.9 ppm/°C in the temperature range of 25 to 100 °C.

This paper presents a fully integrated voltage-reference circuit for implantable devices such as retinal implants. The recently developed retinal prostheses require a stable supply voltage to drive a high-density stimulator array. Accordingly, a voltage-reference circuit plays a critical role in generating a constant reference voltage, which is provided to a low-voltage-drop regulator (LDO), and filtering out the AC ripples in a power-supply rail after rectification. For this purpose, we use a beta-multiplier voltage-reference architecture to which a nonlinear current sink circuit is added, to improve the supply-independent performance drastically. The proposed reference circuit is fabricated using the standard 0.35 µm technology, along with an LDO that adopts an output ringing compensation circuit. The novel reference circuit generates a reference voltage of 1.37 V with a line regulation of 3.45 mV/V and maximum power-supply rejection ratio (PSRR) of −93 dB.

Power-efficient digital controllers are proposed for wireless retinal prosthetic systems. Power management plays an important role in reducing the power consumption and avoiding malfunctions in implantable medical devices. In the case of implantable devices with only one-way communication, the received power level is uncertain because there is no feedback on the power status. Accordingly, system breakdown due to inefficient power management should be avoided to prevent harm to patients. In this study, digital power controllers were developed for achieving two-way communication. Three controllers—a forward and back telemetry control unit, a power control unit, and a preamble control unit—operated simultaneously to control the class-E amplifier input power, provided command data to stimulators, monitored the power levels of the implanted devices, and generated back telemetry data. For performance verification, we implemented a digital power control system using a field-programmable gate array and then demonstrated it by employing a wireless telemetry system.

On-chip systems are challenging owing to the limited size of the components, such as the capacitor bank in the rectifier. With a small on-chip capacitor, the output voltage of the rectifier might ring if the circuit experiences significant changes in current. The reference circuit is the first block after the rectifier, and the entire system relies on its robustness. A fully integrated dual-voltage reference circuit for bio-implantable applications is presented. The proposed circuit utilizes nonlinear current compensation techniques that significantly decrease supply variations and reject high-supply ripples for various frequencies. The reference circuit was verified using a 0.35 µm complementary metal-oxide semiconductor (CMOS) process. Maximum PSRR values of −112 dB and −128 dB were obtained. With a supply range from 2.8 to 12 V, the proposed design achieves 0.916 and 1.5 mV/V line regulation for the positive and negative reference circuits, respectively.

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