Corneal-thickness spatial profile, corneal-volume distribution, percentage increase in thickness, and percentage increase in volume were different between keratoconic corneas and normal corneas and could serve as indices to diagnose keratoconus and screen refractive candidates. Further studies are necessary to evaluate whether these tomographic indices are more sensitive and specific than the classic Placido-based topography.

<h4>PURPOSE</h4><p>To evaluate corneal biomechanical metrics with tomographic parameters (given by the Oculus Pentacam) and refractive data in a population of healthy Brazilian patients.</p> <h4>METHODS</h4><p>Observational, cross-sectional study of 150 consecutive patients (53 men and 97 women; 260 eyes). Age, gender, central keratometric readings (central K), central corneal thickness (CCT), anterior chamber depth (ACD), spherical equivalent refraction, corneal hysteresis, and corneal resistance factor (CRF) were assessed and analyzed. </p> <h4>RESULTS</h4><p>Mean patient age was 46.5±21.04 years, average central K was 43.59±1.54 diopters (D), CCT was 545.05±35.41 µm, ACD was 2.96±0.52 mm, spherical equivalent refraction was –1.16±3.48 D, corneal hysteresis was 10.17±1.82, and CRF was 10.14±1.8 (range: 5.45 to 15.1). Mean CRF and corneal hysteresis were distinct among gender: CRF 10.326 in women and 9.810 in men (<i>P</i>=.0266); corneal hysteresis 10.421 in women and 9.727 in men (<i>P</i>=.0031). A negative correlation was found between both CRF and corneal hysteresis with age (r=–0.1255, <i>P</i>=.0434; and r=–0.2445, <i>P</i>=.0001, respectively). No association was found between CRF and average central K (r=0.0633, <i>P</i>=.3086), ACD (r=–0.0474, <i>P</i>=.4498), or spherical equivalent refraction (r=0.1028, <i>P</i>=.1061). Corneal hysteresis was not associated with age and average central K (r=0.0572, <i>P</i>=.3573), ACD (r=0.0060, <i>P</i>=.9236), or spherical equivalent refraction (r=0.0975, <i>P</i>=.1253). Corneal resistance factor and corneal hysteresis were positively associated with CCT (r=0.5760, <i>P</i>=0; and r=0.4655, <i>P</i>=0, respectively).</p> <h4>CONCLUSIONS</h4><p>Corneal biomechanical metrics of healthy Brazilian patients were associated with CCT, gender, and age. Corneal steepness, ACD, and spherical equivalent refraction did not affect corneal hysteresis and CRF values in the studied population. [<cite>J Refract Surg</cite>. 2008;24:941-945.]</p> <h4>AUTHORS</h4> <p>From Federal University of Sao Paulo (Fontes, Nosé); Fluminense Federal University, Rio de Janeiro (Ambrósio, Alonso, Velarde); and Renato Ambrósio Eye Institute, Rio de Janeiro (Ambrósio, Alonso, Jardim), Brazil.</p> <p>The authors have no proprietary interest in the materials presented herein. Dr Ambrósio is a consultant for Oculus and Reichert.</p> <p>Correspondence: Bruno M. Fontes, MD, Av das Acacias 150 bl 2 apto 1001, Barra da Tijuca, Rio de Janeiro – RJ, 22776-000, Brazil. Tel/Fax: 21 3151 3599; E-mail: <a href="mailto:brunomfontes@terra.com.br">brunomfontes@terra.com.br</a></p> <p>Received: March 15, 2007</p> <p>Accepted: September 19, 2007</p> <p><b>Posted online: April 30, 2008</b></p>

It is the consensus of the medical community that ocular complications associated with Coronavirus Disease 2019 (COVID-19) are mild, self-limiting, and there are no reports to date of a sightthreatening event. We report a patient with a systemic inflammatory syndrome in the context of COVID-19, with ophthalmological (uveitis), dermatological (erythema and skin nodules), and cardiovascular (edema) manifestations. The anterior uveitis led to an increase in the intraocular pressure that failed to respond to clinical treatment and prompted a surgical intervention to save the vision. To the best of our knowledge, this is the first report of a COVID-19-related ocular hypertension. Timely surgical intervention was key to save the vision in the patient's only eye.

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Purpose: To assess the repeatability of central corneal thickness measurement at the geometrical center (Central Corneal Thickness -CCT) given by the Pentacam High Resolution (HR) Comprehensive Eye Scanner (Oculus, Wetzlar, Germany) over time. Methods: Prospective, single center, observational study. Two separate CCT measurements were taken by the Pentacam corneal tomography exam (CTm) 3 to 12 months apart, and compared. Results: One hundred and sixteen eyes (n=116) of 62 health patients were included in this study. Average CCT in first and last visits was 541.6±37 µm and 543.6±36.9 µm respectively. Mean difference between both measurements was 9.2±6.4 µm, and there was no statistically significant difference in CCT measurement between visits, with good correlation between them (P = 0.057, r 2 = 0,9209). Conclusion: Pentacam (HR) CTm gives repeatable CCT measurements over time.Keywords: Cornea/anatomy & histology; Corneal topography; Biometry/methods; Reproducibility of results; Diagnostic techniques, ophthalmological/instrumentation RESUMO Objetivo: Avaliar a reprodutibilidade da medida da espessura corneana central, no seu centro geométrico, com medidas obtidas pelo sistema Pentacam de Alta Resolução (HR) com o decorrer do tempo. Métodos: Realizado estudo observacional prospectivo em Centro Oftalmológico. Duas medidas isoladas da espessura central da córnea (ECC) foram realizadas com exame de tomografia do segmento anterior Pentacam HR em períodos com intervalos maiores que 3 e em até 12 meses, sendo então comparadas os resultados. Resultados: Cento e dezesseis olhos (n = 116) de 62 pacientes saudáveis foram incluídos neste estudo. A média das medidas da ECC na primeira e na última avaliação foi de 541,6 ± 37 µm e 543,6 ± 36,9 µm, respectivamente. A diferença média entre as duas medições foi de 9,2 ± 6,4 µm, e não houve diferença estatisticamente significativa das medida da ECC entre as visitas, com boa correlação entre si (P = 0,057, r2 = 0,9209). Conclusão: O Tomógrafo de Segmento Anterior Pentacam HR apresentou medidas de ECC reprodutíveis ao longo do tempo.