A facile and highly efficient iodine-promoted strategy has been delineated for the synthesis of indolo and pyrrolo [1,2-a]quinoxaline derivatives via oxidative Pictet-Spengler type of amino cyclo-annulation reaction using natural amino...
A facile and highly efficient route towards 3-aryl-1,2-dihydroacridine derivatives from an aldol adduct of o-nitrobenzaldehyde and cyclohexenone derivatives has been described. In situ generated nickel boride was found to be...
A mild and efficient approach for the synthesis of diversely substituted quinoline and quinoline-2-one derivatives has been disclosed. In situ-generated nickel boride was proved to be an effective promoter of the reductive cyclization reaction. Broad substrate scope, mild reaction condition, consistent yield and wide range of functional group tolerance are the other notable features of the newly discovered reaction. A large number of quinoline and quinoline -2-one derivatives may be prepared from milligram to multigram scale employing this intramolecular reductive cyclization protocol.
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