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Diabetes Mellitus (DM) is one of the leading causes of deaths worldwide and is becoming an epidemic in many countries. Sedentary lifestyles, less physical activity, environmental and genetic changes are some of the factors which are responsible for the disease. It is putting a lot of economic burden especially on developing and under developed countries. Hence there is a dire need for the management of this disease. The use of current available therapies is associated with one or more side effects or financial burden. From the past few years, pyrrolidine derivatives have grabbed much of the attention of the researchers for the development of the novel molecules that can be used as a drug candidate for the treatment of Diabetes Mellitus. The current review attempts and aims at compiling the important work done in this relevant area which will help the researchers to design and synthesize the novel Pyrrolidine derivatives as antidiabetic agents with desired clinical outputs.

Bacterial infections are increasingly epitomizing major global health concerns, with rising death rates. Since the most complete assessment of the worldwide impact of antimicrobial resistance to date, with over 1.2 million people dead in 2019 as a direct result of antibiotic-resistant bacterial infections. The majority of antimicrobial drugs have been associated with a multitude of adverse effects including financial costs as well. Pyrrolidine derivatives have sparked the interest of researchers to create novel synthetic molecules with minimal side effect and drawbacks. To close the research gap, the current review discusses the synthetic compounds with active pyrrolidine scaffolds, critical findings and most crucially the structure–activity relationship that affects the activity of the ring over the last one and half decade.

Scarcity of water in this world can be solved by removal of salinity from sea-water but this salinity removal is usually a costly and tedious task. In this work an efficient process has been developed for desalination of water using food waste materials which is completely eco-friendly and economic. A large number of starch rich food materials have been employed for the purpose of desalination of water and it was observed that all of them are effective to remove the salt contained from water, however it was observed that all of those food materials were not equally effective to remove salt contained. Cornflour was seen to be most effective which can remove salinity from sea water up 75-80%. This technology has a great prospect to evolve as a novel and green method for the purpose of desalination of water in near future.