No abstract

Circular RNAs (circRNAs) are novel rising stars of noncoding RNAs, which are highly abundant and evolutionarily conserved across species. Number of publications related to circRNAs increased sharply in recent years, representing emerging focuses in the field. Therefore, tools, pipelines and databases have been developed to identify and store circRNAs. However, there is no existing tool to visualize and explore circRNAs. Therefore, we introduce CircView, a user-friendly visualization tool for circRNAs detected from existing tools. CircView enables users to visualize circRNAs and to quantify number of samples with detected circRNAs. CircView allows users to explore circRNAs detected by unique or multiple tools. Furthermore, CircView allows users to view the regulatory elements, such as microRNA response elements and RNA-binding protein binding sites. CircView is a unique tool to visualize and explore circRNAs, which helps users to better understand potential functions of circRNAs and design the functional experiments.

No abstract

Due to the spectrum varying nature of cognitive radio networks, secondary users are required to perform spectrum handoffs when the spectrum is occupied by primary users, which will lead to a handoff delay. In this paper, based on the multi-armed bandit framework of medium access in decentralized cognitive radio networks, we investigate blind spectrum selection problem of secondary users whose sensing ability of cognitive radio is limited and the channel statistics are a priori unknown, taking the handoff delay as a fixed handoff cost into consideration. In this scenario, secondary users have to make the choice of either staying foregoing spectrum with low availability or handing off to another spectrum with higher availability. We model the problem and investigate the performance of three representative policies, i.e., PRE , SL(K), kth-UCB1. The simulation results show that, despite the inclusion of the fixed handoff cost, these policies achieve the same asymptotic performance as that without handoff cost. Moreover, through comparison of these policies, we found the kth-UCB1 policy has better overall performance.