The diameter of the echogenic response observed with intraoperative sonography during radiofrequency ablation of the cirrhotic liver correlates closely with the mean diameter of the subsequent area of tissue necrosis. However, the solitary diameter of the echogenic response as measured in our study was often greater than the smallest diameter and less than the largest diameter of the area of tissue necrosis. Therefore, the echogenic response associated with radiofrequency ablation of the cirrhotic liver should be viewed only as a rough approximation of the area of induced tissue necrosis; the final assessment of the adequacy of ablation should be deferred to an alternative imaging technique.
Ablation area is increased significantly with hepatic blood flow occlusion in the human cirrhotic liver. This result may have application in the treatment of larger (>3 cm) hepatic malignancies.
The red (Solenopsis invicta) and black (Solenopsis richteri) imported fire ants (IFA) are a common cause of venom allergy in the southeastern United States. Hypersensitivity to stings of native fire ants is less common, although anaphylaxis has been reported to various native Solenopsis species. There have been numerous reports of indoor stings caused by IFA, including in nursing homes and private residences. The following is a report of fatal anaphylaxis to a native fire ant sting in an infant that occurred indoors at a daycare facility. A 3-month-old female was left unattended on a bed. The caregiver had heard the child crying, but attributed this to colic. A short time later, the caregiver found the child apneic and covered with ants. Emergency medical services were summoned, and resuscitation attempts were unsuccessful. Postmortem examination revealed approximately 40 erythematous lesions without pustules. Examination of the respiratory system was notable for congested parenchyma and mild laryngeal edema. Laboratory studies revealed an elevated tryptase of 23.9 ng/mL and radioallergosorbent test (RAST) of 1.4% specific IgE antibody binding to Solenopsis richteri venom. RAST for specific IgE antibody binding to Solenopsis invicta venom was negative. Ants recovered from the scene were identified by an entomologist as Solenopsis xyloni, a native fire ant endemic to the southwestern United States. Native fire ants have features that distinguish them from IFA. Some native species do not build mounds, and stings may not result in pustules characteristic of IFA. There is significant cross-reactivity among the venoms of Solenopsis species, although some species' specificity exists for the Sol 2 allergen. Testing and treatment with IFA whole-body extract is likely to be to be effective for native fire ant allergy. A mixture of S. invicta and S. richteri extracts should be considered when native fire ant species are presumed to cause the primary sensitization to reduce the chance that species-specific reactivity is missed.
A 19-year-old G1P0 Caucasian woman died 8 days postpartum because of the subinvolution of the uteroplacental arteries. Microscopic examination of the placental implantation site revealed large, dilated spiral arteries containing partially occluding thrombi in the superficial myometrium. The presence of cytotrophoblasts within and surrounding the spiral arteries was confirmed by low molecular weight cytokeratin immunohistochemistry. Infection of the Cesarean section incision site was demonstrated by the growth of Staphylococcus aureus and Streptococcus agalactiae Group B in the wound as well as the intrauterine blood clot. Although subinvolution of the placental site may be a cause of delayed postpartum hemorrhage and significant morbidity, the underlying pathophysiologic mechanism is unknown.
The authors report the case of a 47-year-old black man with a history of multiple sclerosis who was found dead in a bathtub, head above water, with a body temperature of 105.7 F. Results of a complete autopsy and toxicologic screen were negative. Individuals with multiple sclerosis, if immersed in hot water, develop motor weakness, which may be so severe as to prevent them from getting out of the water, whether they be in a bathtub or whirlpool bath. In this case, the individual was trapped in a bathtub in which there was a continuous flow of hot water. This overwhelmed an already impaired thermoregulatory mechanism, causing hyperthermia and death.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.