Raman and infrared (IR) studies of Na-hyaluronate films have been performed as a function of relative humidity (RH) and temperature. These data show a number of vibrational modes. Certain of these modes are evident in both the Raman and IR data. Changes in the Raman spectra are observed at the order-disorder phase transition (between 84 and 90% RH) and suggest that the molecular conformation changes at the phase transition.
Complexes of NaDNA with the bipyridyl-(ethylenediamine)platintum(II) (abbreviated [(bipy)Pt(en)]2+) molecular ion have been studied in solution via ultraviolet absorption experiments at 260 nm between 50 and 90 degrees C. These measurements, performed as a function of the molar ratio of the [(bipy)Pt(en)]2+ complex to DNA base pairs, show that the stability of the DNA double helix is increased by the formation of the DNA.[(bipy)Pt(en)]2+ complex: at a molar ratio of 0.33, the temperature at which the DNA double helix separates into two single strands is increased by about 15 degrees C.
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