The original publication of this paper contains an error. Abstract sentence number 5 should be: Ileum malondialdehyde, advanced oxidative protein products, protein carbonyl and tumor necrosis factor-alpha were assessed as biomarkers of lipid peroxidation, protein oxidation and inflammation respectively along with superoxide dismut-ase, catalase, and glutathione peroxidase activities as enzy-matic antioxidants. Abstract sentence number 8 should be: Oxidative and inflammatory stresses assessment in the ileum of rats revealed that aluminum and ionizing radiation

The use of aluminum chloride (AlCl 3) as in purification of water and the exposure to ionizing radiation (IR) in therapeutic treatments are believed to be relatively safe. However, their combined effects remain unclear. The aim of the present study is to investigate the effects of concomitant exposure to aluminum chloride and gamma radiation on the histological and ultra-structural pattern of the crypt Paneth cells (PC) of the small intestine in albino rats. Materials and methods: Forty male albino rats were divided randomly into four groups (n ¼ 10). Group 1: Control group, Group 2: Aluminum treated group (Rats received a daily a dose of 0.5 mg of AlCl 3 per kg of body weight/day), Group 3: g-Radiation group (rats are exposed to a total dose of 8 Gy in 4 fractions of 2 Gy/week) and Group 4 Rats exposed to AlCl3 and exposed to g-Radiation. Animals were sacrificed after 4 weeks, one day after the last radiation dose. Results: Histological and ultra-structural studies in small intestine showed that exposure to grays induced alterations in PC including apoptotic nuclei, presence of injury in secretory granules and completely damaged organelles at the sites of bacterial translocation in the crypt of lumens. Aluminum exposure during irradiation potentiate the damage notified by abnormal PC morphology, dilation the crypt's lumen and erosions of its villi with increased apoptosis in the crypt cells and appearance of homogenously electron-lucent granules. Conclusions: It is concluded that concomitant exposure to aluminum and IR increased detrimental structural changes in PC of rat intestine due to their combined effect. It is thus recommended to limit the intake of aluminum when human are at risk of over exposure to ionizing radiation.

The present work was conducted to investigate the histological and ultra-structural changes in the kidney tissues of male albino rats due to the exposure of gamma-radiation and to investigate tissue-protection from the damaging effects of gamma-radiation using a natural product namely, Beta-carotene. The histological studies revealed progressive pathological lesions in the kidney of whole body γ-irradiated rats; as represented by severe damage in glomerular tuft and increase in masengal cells with wide Bowman's space and sever hemorrhagic areas between degenerated renal tissue, and renal tubules exhibited various degrees of degeneration. The ultra-structural studies revealed that epithelial cells lining the proximal and distal convoluted tubules exhibited an increase in the swelling mitochondria, dilation in the rough endoplasmic reticulum and electron dense in the nuclear chromatin. Thickness in basement membrane, dilation of infolded, and damage of brush border of the proximal tubules were also observed. The treatment with β-carotene pre-exposure to gamma radiation attenuated most of these changes. Therefore, the present study has implication for the potential use of β-carotene as a radioprotector.

The original publication of this paper contains an error.Abstract sentence number 5 should be:Ileum malondialdehyde, advanced oxidative protein products, protein carbonyl and tumor necrosis factor-alpha were assessed as biomarkers of lipid peroxidation, protein oxidation and inflammation respectively along with superoxide dismutase, catalase, and glutathione peroxidase activities as enzymatic antioxidants.Abstract sentence number 8 should be:Oxidative and inflammatory stresses assessment in the ileum of rats revealed that aluminum and ionizing radiation

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