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We have recently reported that sickle cell hemoglobin (HbS) is found at a significant frequency among the inhabitants of Mauritius Island.' In addition, we have established that although the frequency for the p" gene is higher among individuals of African descent (Creoles), it is also found, at significant frequency, among the descendants of Indian immigrants. Because clinical and genetic data have shown that sickle cell disease (SS) linked to the Arab-Indian haplotype is more benign than any of the three different types of African sickle cell disease (Senegal, Benin, and Bantu),' it is important to define the type of sickle cell anemia present in Mauritius Island. In this particular case, the question can be framed in the following way: Did all the p' CORRESPONDENCE

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