The attenuating potential of Trévo Dietary Supplement (TDS), a multi-herbal health drink containing 174 ingredients on caffeine-induced sperm toxicities was studied on albino rats. Thirty healthy male albino rats of 12 weeks old were divided into five groups with six rats in each group using a Completely Randomized Design (CRD). The experimental animals were treated with combinations of caffeine and TDS orally. The treatment lasted for 65 days. Results indicated statistically significant (p<0.05) decreases in weight of testes and epididymis, epididymal sperm viability, motility and count in caffeine treated rats. There was a concomitant increase in sperm head abnormalities in caffeine treated rats. However, TDS effectively attenuated the caffeine induced sperm toxicities in albino rat models in a dose dependent manner.

Tigernut is consumed by humans and livestock. It also has many medicinal uses. There is growing evidence of decline in human sperm count and quality. Hence, this study seeks to evaluate the effect of Aqueous Extract of Tigernut (AET) on testosterone level, weight of epididymes and testes, sperm count, semen pH, sperm motility, sperm viability and sperm head abnormalities in male rats as a model. The rats were divided into four groups of six rats each. The rats were treated with AET at 0.0, 0.6, 1.2 and 1.8 g kgG 1 b.wt. dayG 1 , respectively for nine weeks. After which, the rats were sacrificed and assessed for the parameters. The AET had a dose-dependent effect on all the parameters. In conclusion, AET has the capability of increasing the weights of the testes and epididymes, sperm count, sperm quality and testosterone level. Hence, AET could be used as a possible fertility booster and to attenuate sperm toxicity.

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