Agradecimentos.-Ao Médico Veterinário H. Pradebon pelas ilustrações das lesões macroscópicas.

The rhinitis and granulomatous lymphadenitis was characterised histopathologically by caseous necrosis with proliferation of connective tissue, a neutrophilic and eosinophilic infiltrate, epithelioid cells, multinucleate giant cells, and irregular, moderately septate and ramified hyphae, frequently surrounded by abundant granular and eosinophilic material with radial disposition (Splendore-Hoeppli phenomenon). Lesions from the dorsal and lateral regions of the nose were collected aseptically and transported to the laboratory at room temperature. The samples were placed on to 2 per cent Sabouraud's dextrose agar and incubated at 37°C. Forty-eight hours later, the cultures demonstrated a slight growth of white colonies with submerged root-like elements. Later, it was possible to observe organisms morphologically compatible with P insidiosum following the induction of zoosporo genesis, performed as described by Santurio and others (2003). The identity of the pathogen was confirmed in all four cases through the amplification of DNA by PCR, as described by Rodrigues and others (2006). The extensive ulcerative lesions observed in the sheep resembled the cutaneous lesions described in sheep by Tabosa and others (2004), in horses by Alfaro and Mendoza (1990), in dogs by Thomas and Lewis (1998) and in cattle by Santurio and others (1998). The histopathological findings of granulomatous eosinophilic lesions with many giant cells and Splendore-Hoeppli material involving P insidiosum hyphae are consistent with those observed in previous studies involving sheep from northeastern Brazil (Tabosa and

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