Applying an active intravascular MR catheter device that allows signal transmission from the catheter tip requires special means to avoid radiofrequency-induced heating. This article presents a novel, miniaturized all-optical active MR probe to use with real-time MRI in minimally invasive interventions for catheter guidance and intravascular imaging. An optical link transmits the received MR signals from the catheter tip to the MR receiver with inherently radiofrequency-safe optical fibers. Furthermore, power is supplied optically to the transmitter as well. The complete integration into a small tube of 6-Fr (2-mm diameter) size with a 7-Fr (2.33-mm diameter) rigid tubing was realized using chip components for the optical modulator and a novel miniaturized optical bench fabricated from silicon substrates with 3D self-aligning structures for fiber integration. In MRI phantom measurements, projection-based tip tracking and high-resolution imaging were successfully performed with the optical link inside a 1.5-T MRI scanner. Images were obtained in a homogeneous phantom liquid, and first pictures were acquired from inside a kiwi that demonstrates the potential of the MR-safe optical link. The signal-to-noise ratio has significantly improved compared with former systems, and it is demonstrated that the novel optical link exhibits a signal-to-noise ratio comparable to a direct electrical link.

Magnetic resonance imaging (MRI) is a safe and reliable medical imaging method providing good soft tissue contrast while avoiding harmful ionizing radiation. It is highly desirable to use the MRI technology for interventional procedures. However, due to resonance effects that can result in tissue heating, long conducting cables must be avoided. Motivated by the need for more radio-frequency (RF) safety, we developed an optical transmission system for active intravascular MRI devices. An optical transmitter sends the MR signal via an optical fiber. A miniature optical modulator was designed to be integrated into a catheter tip. Furthermore, power is supplied optically to the transmitter. This system can target new medical applications, due to safe catheter tracking and safe intravascular imaging.

Mechanical and electrical properties of electroplated copper films were investigated to be used in an active tracking system for the patient-safe localisation of a catheter in intravascular interventions using magnetic resonance imaging. For this system spiral micro coils with high aspect ratio are fabricated on a planar polyimide foil to be wrapped around a catheter tip. Due to this special assembly method the coils and the copper, respectively, have to withstand high mechanical forces. The influence of the electroplating parameters as current density and shape, temperature and sample motion on the mechanical and electrical properties is investigated. These samples were characterised using nanoindentation, tensile tests, laser profiler and four-point prober. Results show that a low constant current density at a temperature of 40°C and sample motion generate flexible and high-Q copper coils.

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