About 25% of ischemic strokes remain without an established cause. The article describes the characterization of some hereditary and acquired thrombophilias, which play a significant role in genesis of stroke. One of the ways to solve the problem of etiological diagnosis of thrombotic states is to identify the markers of hereditary or acquired pathology and to conduct molecular genetic typing of the hemostasis system factors. Thrombophilia screening is required for all patients with ischemic strokes of unknown etiology.

The data of 61 medical cards of patients with multiple sclerosis has been analyzed. 47,54% of patients reported pain as a symptom of multiple sclerosis, following types of pain were observed: neuropathic pain (оngoing extremity pain, Lhermitte's phenomenon), nociceptive pain (headache, back pain) and mixed pain (painful tonic spasms, spasticity pain). Only 17,24% of patients received therapy to treat pain.

60 patients after a hemispheric ischemic stroke (IS) were examined. Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), Trail Making Test A and B (TMT), and the Clock Drawing Test (CDT) were used for the cognitive status assessment. A decrease in the MMSE, FAB and MoCA score compared to the control group (CG) (p<0.05) was observed, with probable differences mainly in the domains of attention (p<0.05) and executive functions (p<0.05). An increase in the time of task execution by 45.5% was detected for TMT A (p <0.05) and 61.9% for TMT B (p <0.01), and violation of CDT performance compared to the CG (p<0.05). Thus, the study of cognitive status using TMT and CDT may be recommended for timely detection of the initial executive functions impairment.

No abstract

60 patients after a hemispheric ischemic stroke (IS) were examined. Mini Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Frontal Assessment Battery (FAB), Trail Making Test A and B (TMT), and the Clock Drawing Test (CDT) were used for the cognitive status assessment. A decrease in the MMSE, FAB and MoCA score compared to the control group (CG) (p<0.05) was observed, with probable differences mainly in the domains of attention (p<0.05) and executive functions (p<0.05). An increase in the time of task execution by 45.5% was detected for TMT A (p <0.05) and 61.9% for TMT B (p <0.01), and violation of CDT performance compared to the CG (p<0.05). Thus, the study of cognitive status using TMT and CDT may be recommended for timely detection of the initial executive functions impairment.