Multifocal tuberculosis (TB) is rare. It occurs especially in immunocompromised patients. Association with skin involvement is rarer, and few cases are reported in the literature. The present study reports 7 cases of multifocal TB with cutaneous localization in immunocompetent patients. Cutaneous forms of TB included in this series are: gummas, scrofuloderma, vasculitis TB and lupus TB. The patients had at least two extra skin locations, namely: osteoarticular, lung, pleural, scrotal, muscular, digestive, laryngeal, nodal and splenic locations. These patients had no context of immunosuppression which is uncommon, but should be kept in mind, especially in endemic countries.

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Background: Lipomas are common benign soft tissue, however intramuscular lipoma, is an often misdiagnosed clinical entity. The aim of this case is to present an atypical infiltrating lipoma and discuss its diagnostic and therapeutic features.Clinical features: A 24 year-old patient presented to our consultation with a swelling of the right lower limb from childhood and gradually increasing in size. Clinical examination revealed a firm and extended swelling along the leg, thigh and foot giving an aspect of monomelic hypertrophy. There were no signs of vascular or nerve compression.Intervention and outcome: Pathological study showed a lipoma. Magnetic resonance imaging (MRI) of the right lower limb objectified a large infiltrating lipoma affecting muscles of the posterior compartment of the thigh and the right leg with no signs of malignancy. The diagnosis of intramuscular lipoma was done. The surgery was proposed but the patient refused.Conclusion: This case report described an adult female patient with an unusually intramuscular lipoma where magnetic resonance imaging was playing an important role in the diagnostic. Indeed the intramuscular is a benign fatty tumor with characteristic appearance on MRI. Its management should be considered in multidisciplinary collaboration. Ó 2015 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

L'hamartome lipomateux superficiel de Hoffmann-Zurhelle est une tumeur bénigne souvent congénitale. Histologiquement, il est caractérisé par la présence hétérotopique de cellules adipeuses quelquefois lipoblastiques autour des trajets vasculaires dermiques. Nous rapportons une nouvelle observation de forme multiple à révélation tardive chez une femme âgée de 31 ans sans antécédents pathologiques notables qui a été adressée à la consultation pour des papules et tumeurs asymptomatiques de couleur chaire se regroupent en placards à disposition linéaire et zostèriforme au niveau de la face externe de la cuisse droite depuis l’âge de 13 ans, augmentant progressivement de taille. L’étude histologique d'un fragment biopsique avait montré un épiderme régulier, plicaturé et kératinisant, soulevé par un tissu fibro-adipeux abondant incluant quelques vaisseaux sanguins aux dépens du derme moyen. Ces données cliniques et histologiques ont permis de retenir le diagnostic d'hamartome lipomateux superficiel. Une exérèse chirurgicale des tumeurs de grande taille a été proposée complété par le laser CO2 pour le reste de lésions cutanées. L'hamartome lipomateux superficiel est une lésion bénigne sans potentiel de malignité. L'exérèse chirurgicale peut être proposée si la lésion est gênante ou dans un but essentiellement esthétique.

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