A research study was carried out during Rabi, 2020-21 at Crop Research Centre (CRC), School of Agriculture, ITM University, Gwalior (MP) to investigate the response of barley crop (Hordeum vulgare L.) to irrigation scheduling and nutrient management. The study was carried out in split plot design with irrigation scheduling at different crop growth stages and nutrient management. The main plots consisted of 3 irrigation treatments viz., I0: No irrigation; I1: Irrigation at CRI stage; I3: Irrigation at CRI and tillering stages and sub plots consisted of  four nutrient management treatments viz., N1, N2, N3 and N4. The results of the study revealed that irrigations scheduled at CRI and late tillering stages recorded maximum grain yield (4309.50 kg ha-1) which was 28.90% and 20.90% significantly higher than barley plants received no irrigation and one irrigation at CRI stage, respectively. Among nutrient management, application of 100% NPK with foliar application of 19:19:19 at 30 and 60 days after sowing (DAS) registered significantly higher yield attributes and seed yield of barley (4064.40 kg ha-1) while the treatment combination, two irrigations and 100% NPK with foliar application of 19:19:19 fertilizer at 30 and 60 days after sowing fetched maximum gross (₹ 89256.00/ha) and net returns (₹ 60836.00/ha) and B:C ratio of 3.15.