Acalypha indica Linn. (Family; Euphorbiaceae), commonly known as Indian copper leaf in English and other vernacular names includes, Kuppameni, Kuppi and Harittamanjari. The whole plant of A. indica is used in the traditional medicinal system to treat various diseases. In Ayurveda, A. indica used as a laxative, anthelmintic, emetic, expectorant and also used to treat scabies, earache, syphilitic ulcers and snake bites. In Siddha medicine, A. indica is used to treat diseases associated with teeth and gums, stomach aches, irritations, burns, wheezing and respiratory diseases. This plant has been studied for antidiabetic, wound healing, postcoital infertility, antivenom, antiulcer, antimalarial, anti inflammatory, antimicrobial, alphaamylase inhibitor, neuroprotective and antioxidant activities. Hence the current study has been assumed to explicate the anxiolytic and anticonvulsant effect of methanolic extract of Acalypha indica Linn. MATERIALS AND METHODS Plant material The whole plant of Acalypha indica was collected from Hyderabad, Telangana in November and was identified taxonomically and authenticated by P. Suresh Babu, Head Department of Botany, New Government Degree College, Kukatpally. Preparation of methanolic extract The whole plant of Acalypha indica was collected, cleaned, dried under shade for about six days and coarsely powdered in a mixer grinder. The powdered material was stored and taken up for the Soxhlet extraction process. The 300 g of the powdered plant is packed in the Soxhlet