The process of native blood coagulation was studied with the resonant-acoustic method using the technology of low-frequency piezothromboelastography. It is shown that the experimental curve of time dependence of the piezoelectric sensor signal amplitude reflects the change in the rheological properties of blood during coagulation. A formula is obtained that relates the change in the concentration of thrombin to the rate of change in the complex coefficient of blood viscosity. A method has been developed for assessing thrombin concentration during fibrinogenesis based on the technology of piezothromboelastography using a resonant-acoustic method to determine the viscoelastic properties of whole blood. The results of calculating the thrombin concentration by this method are compared with the results of the thrombin generation test.

We carried out an experimental and theoretical study of the electrical conductive properties of the tissues of the vestibular labyrinth. Using the theory of dynamic systems and experimental data on measurements of the amplitudes of the electrical signal at the end of the vestibular nerve, we calculated the transfer function of the vestibular labyrinth and investigated its frequency dependence. It is shown the transfer function tends to its asymptotic value with increasing frequency. We found that the transfer function of the vestibular labyrinth for stimulating impulses emanating from the electrode located in the posterior semicircular canal is significantly less than for stimulating impulses from the electrodes located in the superior and horizontal semicircular canals.