Relevance. Anatomical and functional disorders in congenital clefts may be various. Their severity depends on the cleft size and on the combination of a cleft lip with an alveolar cleft. Alveolar cleft bone grafting (ACBG) is one of the most important surgeries for patients with cleft lip and palate rehabilitation. The study aimed to analyze the results of alveolar cleft bone grafting in various age groups, summarizing the available data and supplementing them with our own experience.Materials and methods. In our clinic, 488 patients of different ages (from 4 to 18 years old), including patients with bilateral clefts, underwent ACBG.Results. The result analysis showed the time of surgery should depend not on the child's age but on the orthodontic preparation of the child for ACBG.Conclusion. The literature data and our experience allowed us to develop indications for ACBG at different ages

Relevance. Branchio-oto-renal syndrome (also known as Melnick-Fraser syndrome) is a rare syndrome characterized by hearing loss, renal malformations and branchial cyst (fistula) association. The article describes a clinical case of a boy with an atypical clinical picture of branchio-oto-renal syndrome.Material and methods. The patient was admitted to our clinic with acute inflammation, complaints of hearing loss and a fistulous tract in the right retromandibular region.Results. After the acute inflammation resolution and necessary investigations, the patient underwent a fistulectomy for diagnosis verification. We analyzed the patient routing from the first presentation to the patient's GP to the final diagnosis in our clinic. Based on this clinical case result analysis, we offered optimal diagnosis and treatment tactics for patients with Melnick-Fraser syndrome.Conclusion. Correct branchio-oto-renal syndrome diagnosis requires careful history taking, clinical examination and multidisciplinary team involvement. This approach will allow the patient to receive a full range of treatments with quality-of-life preservation.

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