No abstract

Both chronic renal failure (CRF) and heart failure (HF) can predispose to pressure load or volume overload with subsequent elevation of serum brain natriuretic peptide (BNP) levels. This study tends to evaluate the role of BNP as a predictor of left ventricular function among patient with chronic renal failure on maintenance hemodialysis. Methods: This is a perspective cross-sectional study, including 89 (45 males and 44 females) patients on maintenance hemodialysis followed up for six months. BNP level, glomerular filtration and body mass index of the patients were measured and left ventricular function (EF%) was detected by echocardiography at the start of the study and after three and six months between October 2016 and April 2017.Results:Of 89 patients, 13 were underweight, 56 had a healthy weight, and 20 were overweight. There was a significant negative association between BNP level and both EF% and BMI (P<0.001, P<0.001) respectively. During the follow up of these patients there was a clear trend for BNP to be higher among patients with impaired left the ventricular function. There was also a strong inverse association between BNP level and GFR (P <0.001).Conclusion: BNP levels show a strong inverse association with EF%, BMI and GFR in patients with CRF. Currently, BNP widely used by most health institutions to predict left ventricular function. However, both BMI and GFR considered a significant confounder of BNP measurement in patients with compromised renal status.

Through the current research, a study of the nuclear composition and the form of even isotones movements – those of the even atomic weight between 178 – 188, after specifying the dynamic symmetry of each nucleus using the first prototype of the interactive bosons (IBM-1), the intrinsic values as well as the intrinsic vectors were calculated using the (IBM-code) program.It also calculated the probability of the quadrant-polar, electric movement that are B(E2) as well the quadrant-polar, electric torque (QL)using the (IBMT-code) program.The 130Ba isotope with 56 protons and 74 neutrons, has the number of bosons is 7 and the ratio R 4 1 + / 2 1 + is 2.5235, the levels 2 1 + , 4 1 + , 6 1 + , 8 1 + , 2 2 + , 0 2 + and 2 3 + , with energies 0.3574, 0.8914, 1.6021, 2.4894, 0.8971, 1.1795and1.5369 MeV are in good agreement comparing with the experimental energy. The level 4 3 + , with energy 2 0709MeV compared with the energy experimental 2.0537 MeV. So, this level confirmed in the present work. The levels 10 1 + , 12 1 + , 3 1 + , 4 2 + , 5 1 + , 6 2 + and 8 2 + , with energies 3.5534, 3.5534, 1.6143, 1.6111, 2.5065, 2.5016 and 3.5689 MeV, respectively correspond to cases for which the angular momentum and/or parity of the corresponding states are not well established experimentally. The calculations have been predicted new levels with energies 3.5754, 2 7816.and 3.6689MeV for the angular momentum and parity 7 1 + , 6 3 + and 8 3 + , respectively. From the experimental value of transition B ( E 2 ; 2 1 + → 0 1 + ) , the value of parameter eB (α2) have been calculated for 130Ba isotope and The comparison for 130Ba isotope under study. There is no available experimental transition data to many transitions, Therefore, it has been predicted using IBM-1. In this study, there are a good agreement between the experimental B(E2) values and the IBM-1 calculated generally.

Background: chronic renal failure (CRF) characterized by increased plasma level of brain natriuretic peptide (BNP) due to increase peptide secretion and decrease BNP clearance due to impaired renal function. This peptide is a biomarker of cardiovascular disorders which are the common causes of morbidity and mortality in patients with CRF. The present study tend to evaluate the role of BNP as a predictor of left ventricular function among patient with chronic renal failure on maintenance hemodialysis(HD) with particular concern to dialysis session frequency. Methods: A total of 90 patients with CRF who visited the dialysis unit at Al-Hussein Teaching Hospital in Thi-Qar city for maintenance hemodialysis were included in this study. They were divided into three groups according to the number of dialysis session per week. BNP level, glomerular filtration rate(GFR) of the patients were measured and left ventricular function (EF%) was detected by echocardiography. Results: There was a significant negative association between BNP level and EF% (P<0.001). BNP level was significantly lower in patients with three dialysis session per week in comparison with those patients who perform single session per week (P <0.001). There was also a strong inverse association between BNP level and GFR (P <0.001).Conclusion: BNP levels show a strong inverse association with EF% and GFR in patients with CRF. Patients with frequent dialysis had better left ventricular function manifested by lower BNP level and higher EF% than those patients with less frequent dialysis session.