PTMC is an indolent disease, but does pose a risk for LNM and local recurrence. More aggressive treatment or more frequent follow-up could be considered for patients with unfavorable features (age <45 years, multifocality, ETE), especially in the setting of involved lymph nodes at the time of surgical resection, as these patients may be at an increased risk for recurrence.
Thyroid nodule size is inversely related to malignancy risk, as larger nodules have lower malignancy rates. However, the relationship of size to malignancy varies by FNA status. All nodules (regardless of FNA status) demonstrate a risk trough at ≥2 cm. Nodules subject to FNA show step-wise decline in malignancy rates by size, demonstrating that size alone should not be considered as an independent risk factor. Size at ultrasound shows relatively good correlation with final pathologic size. False negative rates are low in this series. Lesions with the appropriate constellation of clinical and radiographic findings should undergo FNA regardless of size. Both size and FNA diagnosis should influence the clinical decision-making process.
Objective: To evaluate the effect of propolis (a natural herb) against dentine hypersensitivity and to compare their effect with the controls.Methodology: Two databases were selected and searched for the relevant articles published up to 2019. Clinical trials involving propolis with other desensitizing agents and comparing it with controls were included involving patients that possess dentine hypersensitivity along with the extracted teeth. Nine clinical trials from 1999 to 2019 met the criteria involving 169 patients who had sensitivity and 214 extracted teeth were included in this scoping review.Results: Propolis was found to have a better desensitizing results than the controls, except Recaldent ™ which showed better results than Porpolis. Conclusion: Our results support the assertion that propolis is a good option which occludes the dentinal tubules and can relieve the symptoms of dentine hypersensitivity. However more clinical trials and high quality studies are needed to confirm its results in a better way.
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