The objective of this work is to formulate and evaluate a cosmetic herbal face pack for glowing skin by using natural ingredients. With the varying concentrations, four different formulations containing ingredients such as multani mitti, turmeric, aloe vera, sandal wood, orange peel, neem and nutmug; were prepared named as F1 to F4. All prepared formulations were evaluated by different parameters like organoleptic properties and physico-chemical parameters and stability along with irritancy test and microbial load. Among all formulation, F2 was found to be good in physical parameters, free from skin irritation and maintained its consistency even after stability storage conditions and also having microbiological stability.

Nanoscale drug delivery systems are now proposed as an alternative to classical formulations for drug administration, delivery and targeting. For the past few decades, there has been a considerable research interest in the area of drug delivery using particulate delivery systems as carriers for small and large molecules. Nanoscale technologies are beginning to change the foundations of disease diagnosis, treatment and prevention. They have been used in vivo to protect the drug entity in the systemic circulation, restrict access of the drug to the chosen sites and to deliver the drug at a controlled and sustained rate to the site of action. Various polymers have been used in the formulation of nanoparticles for drug delivery research to increase therapeutic benefit, while minimizing side effects. Here, we review various approaches of nanoscale drug delivery system in delivery of drug molecules and therapeutic genes. The article also reveals the concept of DNA nanotechnology as well as nanospore sequencing from nanomedicine

Aim: To establish the wound healing activity of Sesamum indicum L. of seed extract in novel ethosomal vesicles. Methods: The ethosomal vesicles were formulated with prepared seed extract of Sesamum indicum L. by solvent evaporation method and characterized it. The optimized ethosomal vesicles then incorporated into gel base for further in vivo study in wistar rat. The evaluation of the wound healing activity was performed by using two models i.e. incision and excision models. In excision model percentage wound contraction and period of epithelialization were established for both the extracts. In incision model the parameter which was carried out was breaking strength of wounded skin. Results: The results revealed that the percentage wound contraction, period of epithelialization in excision model was enhanced than that of other groups and tensile strength of skin in incision model was similar to that of standard treated group. Keywords: Sesamum indicum L., Wound Healing, Ethosomal gel.

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Nanomedicine is now proposed as an alternative to classical way for diagnosis, imaging agents, delivery and targeting. For the past few decades, there has been a considerable research interest in the area of drug delivery using as different nanoscale carriers for small and large molecules including liposomes, nanoparticles, antibodies etc. There is an urgent need to improve the understanding of toxicological implications of nanomedicines. Particular health risk of nanotechnology application in nanomedicine is still unknown, but researchers are gradually putting up theories to prove that nanotechnology pose many threats to human health as well as the environment. The current mini review presents the pitfalls of growing nanomedicine with nanoscale properties.