Introducti on: Tenia Cruris is the commonest dermatophyte infecti on which is common in men and aggravated by warm humid conditi on Teniarubrum is the main species for the disease 1,2 . Itraconazole and Terbinafi ne are the bett er newer drugs for the therapeuti c opti on due to their effi cacy, convenient and less side eff ect. Itraconazole is a wider spectrum Thiazole group of fungistati c drugs which inhibit sterol 14 α demethylase impairing biosynthesis of fungal ergosterol. Similarly Terbinafi ne is broad specturmallylamine group of fungicidal acti vity which inhibits squalene 2, 3 epoxidase enzyme thus inhibit fungal biosynsthesis of ergosterol [3][4][5] . These two drugs have been needed conventi onally as a pulse and conti nuous therapy. The main aim of this study is to compare the effi cacy of both drugs and to recommend the eff ecti ve treatment in case of Teniacruris. Methods:In this randomized comparati ve study, the effi cacy and safety of oral itraconazole (n=35) and terbinafi ne (n=35), each given for 2weeks, was compared in pati ents with ti neacruris within the period of 1 year study. Results:The fi nal evaluati on at week 4 showed a cure rate of 91.4% for itraconazole and 82.9% for terbinafi ne. No defi nite adverse eff ect was noted. Conclusions:Itraconazolehas high cure rate and less failure rate without side eff ects in comparision toTerbinafi ne.

Introduction: The issues of sexual and reproductive health (SRH) remain the leading cause of ill health among adolescents worldwide and are of growing concern in Nepal. The correct knowledge of condoms is integral part of SRH. The present study was carried out to assess and compare the knowledge about condoms among adolescents in the Kathmandu valley of Nepal. Aim: To study, assess and compare the knowledge about condoms among adolescents in the Kathmandu valley of Nepal. Methods: The study was a cross-sectional questionnaire-based survey. The sample was derived through cluster sampling of the secondary schools in the Kathmandu valley. Schools were selected randomly and two hundred and fifty adolescents were taken from each government and non-government high schools. Result: Altogether 500 adolescents were recruited for this study. A total of 298 (53.0%) participants said that condoms reduced pleasure. Most women don't like to use condoms was agreed by 291 (55.6%) people and it was statistically significant (p value < 0.05) when compared between males and females. Using condoms with new partner is a good idea was agreed upon by 448 (81.0%) participants. Women should ask their partners to use condoms was answered by 480 (88.1%) and discussing condom use with prospective partner is easy was agreed by 417(79.0%) and both the issues were also statistically significant (p value < 0.05). Conclusion: It was found that the knowledge about condoms was not adequate and the knowledge among male participants was in general better than females. Key words: Adolescents, Condom, Sexual and reproductive Health DOI: 10.3126/jnps.v30i1.2455 Journal of Nepal Paediatric Society Vol.30(1) 2010 18-22

Introduction: Dermatological conditions make up a significant burden of hospital visits. This study aims to calculate the prevalence of different dermatological conditions among OPD visits in a tertiary care hospital in Kathmandu, and describe the variation of those conditions with demographic variables and seasons. Methods: This study was performed retrospectively using the data collected in the OPD register of a tertiary level hospital from 14th April 2017 to 13th April 2018. Analysis was conducted using MS Excel 2016 and Statistical Package for the Social Sciences (SPSS) v25. Results: A total number of 24,332 OPD visits were recorded in the year. 54.3% of the visits were made by males and 45.7% by females and most common age group seeking dermatological consultation was 25 to 34 years. Noninfectious dermatoses were more common than infections. The most common noninfectious dermatoses were dermatitis/eczema, urticaria, angioedema and hypersensitivity, and pigmentary disorders in descending order of frequency. The common infectious dermatoses in decreasing order of frequency were fungal, viral, and parasitic/protozoal conditions. The infectious dermatoses were found to be significantly higher in males (p<0.05) while pigmentary disorders, urticaria and angioedema, autoimmune cutaneous disorders, disorders of pilosebaceous units and xerosis were significantly higher in females (p<0.05). Bacterial, fungal and viral infections, eczemas, urticarial/angioedema, papulosquamous disorders, xerosis, neoplasms and vasculitis showed significant seasonal variation. Conclusions: Eczemas and fungal infections are the most common dermatoses. Infectious dermatoses and several non-infectious dermatoses vary significantly with seasons.

Introduction: Human Skin is the largest organ of the body and may mirror the presence of benign/malignant systemic diseases in different ways. The pattern of Skin diseases vary in different parts ofNepal due to differences in socioeconomic and geographic factors. This retrospective study, pattern ofskin disease in Army Hospital likely reflects the pattern of disease in the Kathmandu Valley.Aim: To study, assess and compare the different patterns of skin disease in the patients attending theoutpatient department in the year 2007 and 2008 in the Army Hospital.Methods: This was a retrospective study and all the new cases which were diagnosed in the Department ofDermatology in the years 2007 and 2008 were included. The diseases were classified as Papulosquamous,Vesicobullous, Connectivetissue disorders, Skin and Soft tissue tumours, Infective, Eczema, SexuallyTransmitted Disease (STI), Leprosy and those skin diseases which were not coming under this formatwere classified as others.Result: The total number of cases recorded in the Department of Dermatology were 16828 in the year2007 and 18643 in 2008. It was found that the infective group of disorders were the largest group ofdisease, in the year 2007 a total of 6135 (36.4%) and in 2008 a total of 7883 (42.2%) had suffered from thisgroup of disorders. And the incidence of infective disorder was also statistically significant when both theyears were compared p-Value:0.00, OR:1.16, CI:1.11-1.21. Similarly other large groups were Eczema,papulosqumous and sexually tranmitted disease.Conclusion: It was found that the disease pattern in this study was lead by infective disease followed byeczema, papulosquamous disease and sexually transmitted disease.Key words: Eczema; Papulosquamous; VesicobullousDOI:  10.3126/mjsbh.v9i1.3484Medical Journal of Shree Birendra Hospital Vol.9(1) 2010 14-16

No abstract