Background: Coronary collateral circulation (CCC) is linked to myocardial remodeling severity in patients with chronic ischaemic heart disease (IHD). However its effect on left ventricular reverse remodeling (LVRR) in patients with chronic IHD underwent coronary artery bypass surgery (CABG) has never been reported. Purpose of this study was to investigate the effect of CCC grade on the LVRR event in patients with chronic IHD underwent CABG.
Methods: This prospective cohort study was performed in patients with chronic IHD underwent CABG. The CCC was classified using Rentrop collateral score, i.e low CCC grade (Rentrop score 0 and 1) and high CCC grade (Rentrop score 2 and 3). LVRR event was defined as a reduction in left ventricular end systolic volume (LVESV) of 10% or more, measured by a 3D echocardiography at 1.5 months post CABG compared to the baseline before CABG.
Results: A total of 22 patients (81.8% male) with mean of age 58.6 years old were enrolled. LVRR occurred in 50% patients. LVRR event was significantly higher in the patients with high CCC grade than the low CCC grade patients (p=0.009). The high CCC grade increased LVRR event independently (odds ratio=26.67; relative risk=6.93).
Conclusions: High coronary collateral circulation may increase left ventricular reverse remodeling event in patients with chronic ischemic heart disease underwent coronary artery bypass surgery.
Keywords: coronary collateral circulation; left ventricular reverse remodeling; chronic ischaemic heart disease; coronary artery bypass surgery; 3D echocardiography.
Aims
The tricuspid annulus dilatation is an indication for tricuspid repair concomitant with mitral surgery. The distance between anteroseptal and anteroposterior commissure represents the direction of dilatation provided by surgical measurements. However, none of the standard views of two-dimensional transthoracic echocardiography (2D-TTE) intersect that plane and there is still a lack of study regarding the tricuspid annulus measurements by three-dimensional transthoracic echocardiography (3D-TTE). Therefore, this study aims to determine the agreement between the tricuspid annulus diameter measurement by transthoracic echocardiography and surgical measurement.
Methods and Results
40 patients were included. Measurements of tricuspid annulus diameter by 2D-TTE and 3D-TTE were performed before surgery in parasternal right ventricle inflow (PRVI), parasternal short axis (PSAX), apical 4-chambers (A4C), and multiplanar analysis 3D-TTE views. Surgical measurements were performed during surgery. Agreement between the echocardiography and surgical measurements was analyzed using Bland-Altman and intraclass correlation analysis. Mean difference ± standard deviation (limits of agreement) and ICC of PRVI 2D-TTE vs surgical measurement were 1.35±5.02 mm (-8.48 - 11.18 mm), ICC 0.89, p < 0.001; PSAX 2D-TTE vs surgical measurement were 1.35±5.23 mm (-8.90 - 11.60 mm), ICC 0.88, p < 0.001; A4C 2D-TTE vs surgical measurement were 1.33±3.69 mm (-5.91 - 8.56 mm), ICC 0.93, p < 0.001; septolateral diameter 3D-TTE vs surgical measurements were 1.42±4.41 mm, (-7.22 - 10.06 mm), ICC 0.90, p < 0.001; anteroposterior diameter 3D-TTE vs surgical measurements were -2.695±7.43 mm (- 17.26 - 11.87 mm), ICC 0.68, p < 0.001.
Conclusion
A4C 2D-TTE and septolateral diameter 3D-TTE measurement have an excellent agreement with surgical measurement.
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