® . Results: The results of this work confirm that bovine brucellosis is endemic in Cameroon. With an uneven but wide distribution the study revealed a 4.61% and 16% seroprevalence at the animal-level and herd-level respectively. There was a preponderance of seropositivity in the GHS (87.5%) over the WHPS (12.5%). The extrinsic risk factors investigated were all positively correlated with seropositivity. It was interesting to note that cattle interactivity with sheep and goats (small ruminants), wildlife, herd size, administrative division, history of third trimester abortion, ecological zone, and herd management systems had significant effects on seropositivity. Conclusion:To the best of our knowledge, these findings provide the first factual insight into the seroprevalence of bovine brucellosis and some of its associated risk factors in the most livestock-productive agro-pastoral ecozones of Cameroon.

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