Background: Central nervous system neoplasms represent a   unique, heterogeneous population of neoplasms and include both benign and malignant  tumours. The tumours of central nervous system are reported to be less than 2% of all malignancies. Aim: To study the frequency of intracranial tumours and their histopathological typing and their correlation with several clinical variables such as age, sex and clinical symptoms . Material & Methods: Study Design: Hospital based Prospective observational study. Study area: Dept. of. Pathology, Study Period: 2 years. Study population: patients who presented with signs and symptoms of primary intracranial tumours were examined and followed up for the histopathological diagnosis. Sample size: Study population consisted a total of 68 patients.  Sampling method: Simple Random sampling method. Inclusion criteria: Patients with both benign as well as malignant primary neoplasms of the brain including pituitary tumours. Exclusion criteria: All the spinal cord, calvarial and metastatic tumours were excluded. Ethical consideration: Institutional Ethical committee permission was taken prior to the commencement of the study. Study tools and Data collection procedure: Staining Procedures Adopted: After grossing, proper tissue bits were subjected for routine processing, fixation, dehydration, clearing and embedding in paraffin wax and blocks were made.

Epithelioid sarcoma is an uncommon kind of sarcoma that often affects young individuals and has a preference for distal upper extremity; forearm and hand. This usually begins as slow-growing, painless tumor. It can also be seen as multiple tumours. Lymphatic channels are the primary routes of dissemination for the disease’s recurrence and spread. Using polygonal cells, a biopsy is the preferred technique of diagnosis. Treatment primarily consists of wide resection. Here, we present a case of epithelioid sarcoma involving the wrist of 52-years old female. It was initially diagnosed by imprint cytology. To make an accurate diagnosis in a case with a unique history, it is necessary to consider the clinical presentation, morphologic examination, and a broad panel of immunohistochemical staining.