This study was designed to evaluate the antibacterial activity of Algerian honey and some extracts of Nigella sativa L. seeds against animal wound bacteria. To do this, the preparation of Nigella sativa L. seed extracts was carried out by macerating the seed powder in increasingly polar solvents (ethyl acetate, ethanol and methanol). The antibacterial activity of honey and Nigella sativa L. seed extracts against the bacterial isolates was studied by Agar Well Diffusion Assay. The results showed that the different honey concentrations (20%, 50%, 70% and 100% v/v) were found to be active against all the bacterial isolates. The different Nigella sativa L. seed extracts showed a variable activity at the concentration 300 mg/mL against the bacterial isolates. Ethanolic extract of Nigella sativa L. seeds was found to be active against all the bacterial isolates. Methanolic extract of Nigella sativa L. seeds was found to be active against all the bacterial isolates except Escherichia coli. Also, ethyl acetate extract of Nigella sativa L. seeds was found to be active against all the bacterial isolates except Enterococcus faecalis. In conclusion; Algerian honey (of the region of El-Eulma) and ethanolic extract of Nigella sativa L. seeds can be used as an alternative remedy for the treatment of different animal wounds.

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This review mainly focuses on the epidemiological characteristics of respiratory diseases, abortions, perinatal mortalities and neurological diseases in horses caused by EHV-1 and EHV-4. There are several sources of EHV-1 and EHV-4 which are transmitted by different routes. The latency and reactivation of EHV-1 and EHV-4 play an important role in the persistence of infection with these viruses in the equine population. These viruses are major agents in respiratory diseases in horses. Mares and their foals play an important role in the circulation of these viruses on farms. Abortion and perinatal mortality can take the sporadic or epizootic form. Neurological disease is caused primarily by neuropathogenic EHV-1. Combined epizootics of neurological diseases and abortions are common.