PCOS syndrome is major compatible female problem there for this mini review was focus on the research which are tested the effect of probiotic supplement on PCOS. Methods: In this mini review the was key word such as (PCOS, obesity, lipid profile, testosterone) and used Google scholar and pub med. the study was used 7 article published between (2015-2019). Results: The study was positive result about effect of probiotic on the body weight, lipid profile, sex hormone and oxidative factors. the study was showed more relationship between the 7 articles which are used in this study. Conclusion: This review was showed probiotic positive function on PCOS treatment in the women.

The crude chloroform and methanol extracts of Lepidium sativum seeds belong to family Brassicaceae,were used in this work to study their efficiency to reduce Aflatoxin B 1 in rats. The more effective of chloroformic extract which decreased Aflatoxin B 1 level from 8.7 to 1.0 ppb at a dose of 300 mg/kg body weight comparing with ligalon (Silymarin) which reduced Aflatoxin B 1 to 0.97 ppb in concentration of 100 mg/kg after 5 weeks, followed by methanolic extract at a dose of 300 mg/kg body weight which showed the mean value of 1.2 ppb.Also, the more effective treatments may be Silymarin in concentration of 100 mg/kg followed by chloroformic extract, while methanolic extract of Lepidium sativum seeds was represented middle effect for blood tests of rats injured with Aflatoxin B 1 e.g. Serum marker enzyme parameters (MDA, SOD, ALP and Bilirubin), kidney functions (Creatinine and Urea), liver functions (ALT, AST, Total proteins, Albumin and Globulins), lipid profile (triglycerides, total cholesterol, HDL-c, LDL-c and vLDL-c ) and haematological parameters (HB, RBCs, Plt and WBCs), were determined in injured rats comparing with control rats. It is quite clear that Silymarin is considered synthetic product, so the natural extracts of garden cress are more suitable for usage due to, they considered more safety and economic products, so these extracts can be additive to foodstuffs and therapeutic drugs owing to their multi medicinal benefits.