A natural dye is extracted from turmeric and used to dye cotton at different dyeing conditions. Then the fastness properties of the dyeings with different dyeing techniques are compared. The dye is found to have good saturation and rubbing fastness, but poor washing and light fastness properties on cotton, when applied without any mordant. When dyeing is implemented with mordants, washing and light fastness properties show improvement while rubbing fastness exhibits deterioration. Finally, comparative studies between natural and synthetic reactive dyes reveal that the natural dye has the potential to act as a co-partner with reactive dyes with a few compromises.