The risk factor profiles, management and outcome have significant difference between stroke subsets.

Background: There is a high prevalence of coexisting medical conditions in patients with acute stroke; therefore, clinical investigators often need to adjust for comorbidities when assessing the effect of those risk factors on patient outcome. Objective: This study aimed to determines comorbid risk factors in patients with acute stroke. Methodology: A hospital-based case control study was conducted in Shaheed Suhrawardy Medical College Hospital (ShSMCH) and Dhaka Medical College Hospital between January-June 2011. The cases and controls studied consisted of 175 hospitalized patients with stroke (confirmed by computed tomography scan) and 171 matched-age and sex controls that were hospitalized at the study hospital for condition other than stroke. After obtaining written informed consent from the patient or the closest attendant, all the information included to record were age, sex, monthly family income, family size, family history of CVD death, history of hypertension and diabetes mellitus, ECG change, aspirin intake, blood pressure and heart rate, waist and hip circumference and psychosocial factors. The edited data then analyzed by SPSS V. 16. Result: The most predictive independent variables were history of hypertension (OR 4.056), psychosocial stress (OR 4.90) and increased WHR (OR 3.806) were found significant risk factor for developing stroke. Conclusion: Therefore, to recognize comorbid risk factors and to treat them appropriately is the key to establish primary preventive strategies in non-stroke patients or secondary preventive measures to avoid recurrence in stroke victims. [Journal of National Institute of Neurosciences Bangladesh, 2016;2(2): [84][85][86][87][88]

Background: Visceral Leishmaniasis (VL), commonly known as Kala-azar is a chronic febrile disease occurs widely throughout the world. There are many risk factors which can influence the causation of kala azar in Bangladeshi people. The aim of the present study is to describe the Sociodemographic, household and environmental risk factors of kala-azar among a case series of Bangladeshi patients. Method: This case control study was carried out at inpatient department of Community Based Medical College Hospital, Mymensingh from July 2010 to June 2011, for a period of 1(one) year. The study samples were clinically and parasitologically confirmed kala-azar cases. The controls were rK 39 strip test negative hospitalized cases admitted for other reason. Results: Univariate analysis showed that nature of wall in the main structure, floor of the house, presence of cracks and crevices in walls, presence of a granary inside houses and presence of bamboo trees near houses, were risk factors for kala-azar. Multivariate analysis showed that Presence of cracks and crevices in walls (OR=3.429, 95%CI=1.037-11.338, P =0.043) and presence of bamboo tree around houses (OR=5.652, 95%CI =1.368-23.347, P =0.017) in rural areas of study region, were significant risk factors for kala-azar. Conclusion: These findings have important practical implications because they suggest that on improving housing and environmental conditions in rural areas, may be particularly effective in reducing the incidence of kala-azar and its transmission of infection by sand fly vectors.

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Background: Dyslipidemia contributes to the high cardiovascular risk in end stage renal disease (ESRD) or in dialysis patients; however, it remains an underestimated problem. Objective: To see the extent of dyslipidemia in patients of end stage renal disease i.e. chronic kidney disease (CKD) stage 5 who underwent hemodialysis or peritoneal dialysis procedure. Materials and Methods: This cross-sectional study was conducted from September 2016 to March 2018 Bangabandhu Sheikh Mujib Medical University (BSMMU) on 55 CKD (stage 5) patients where 31 in hemodialysis (HD) (group A) and 24 in continuous ambulatory peritoneal dialysis (CAPD) (group B). Serum lipid profile was estimated in both groups by using the standard laboratory technique. Results: Dialysis adequacy (Kt/V) was found 1.46 for HD patients (group A) and 1.81 for CAPD patients (group B).All serum lipids were higher in amount in CAPD patients than HD patients-total cholesterol (222.3±24.2 mg/dl vs. 198.9±28.4 mg/dl; p<0.05), triglycerides (179.6±24.7 mg/dl vs. 176.6±24.4 mg/dl; p<0.05), HDL cholesterol (40.8±3.90 mg/dl vs. 38.5±4.95 mg/dl; p>0.05) and LDL cholesterol (145.5±22.1 mg/dl vs. 123.2±26.5 mg/dl; p<0.05). Besides, dyslipidemia was more evident in CAPD patients than HD patients, as per raised serum total cholesterol (83.33% vs. 70.97%), raised triglycerides (95.83% vs. 83.87%), raised LDL (100% vs. 77.42%) and lowering of HDL cholesterol (87.5% vs. 80.65%) were found more in group B in comparison to group A. Conclusion: Dyslipidemic risk factors are highly evident in dialysis patients and the extent of dyslipidemia is observed more in CAPD than HD patients. KYAMC Journal Vol. 11, No.-3, October 2020, Page 113-117