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Background: COVID-19 remains an emerging pandemic that continuously poses an alarming threat and challenge to economic, social and well-being of the people throughout the world. It also remains an evolving disease which complete pathogenesis that translates into clinical features is only just emerging by each second of the day. There have been observations about the emerging trends of the disease in Nigeria like in any other country in the world where there is outbreak. This study examined from evidence-based literature the emerging pathogenesis of COVID-19 and important points of concern of the disease in Nigeria. Materials and Methods: The paper reviewed published articles in PubMed and Google Scholar using search terms ‘COVID-19” and “SARS-CoV-2”, as well as searched for general COVID-19 information on internet. Results: The result summarized literature on emerging pathogenesis of COVID-19 and important points of concern as well as research questions as to the peculiar trends of the disease in Nigeria. Conclusion: Pathogenesis of COVID-19 remains an emerging knowledge and there are many important research questions that need to be scientifically answered for a successful containment of COVID-19 in Nigeria. It is recommended that all members of intellectual research communities should join the fight against COVID-19 pandemic.

Safety practices on Nigerian construction sites cannot be overemphasized because it plays a huge role in the timely deliverability of projects and indeed the wellbeing of the construction site worker who bears the direct impact of construction site hazards which often most times is life threatening in the event that safety practices on construction sites are not strictly adhered to. The research objectives were to establish that construction workers attitude towards safety practices is determined by their understanding of construction site risks, safety rules and general work procedures; also to determine the extent of the relationship between poor safety culture and increased rate of unsafe acts in the Nigerian construction industry. It focused on workers of medium sized Construction Companies and specialized contractors operating within Benin City, South-South Nigeria and Gombe Metropolis, NorthEast Nigeria. The duration of study is between March 2017 and November 2018. Primary and secondary data were both collected through comprehensive literature review, personal interviews, structured questionnaire and observations. Five hundred (500) questionnaires (250 each administered within the study areas) were distributed to workers of construction companies to access their perception and understanding of safety practices on construction sites workplaces. Ranking on five point scale was used to analyze the questionnaires and to measure a range of opinions from most important to least important. The results shows Lack of safety training was ranked the highest; while Shortage or absence of safety equipments was ranked the lowest cause of workers' accidents on construction sites. 65% of the respondents affirmed that their companies practice safety programs while 35% affirmed otherwise. Amongst the Benefits of practicing Safety culture on construction sites, reduced accident occurrence is ranked the highest while the keeping of accidents and near misses records in relation to improving safety and preventing construction sites accidents ranked lowest. As a good safety practice on construction sites, it is the responsibility of the construction company and indeed its workers to identify unsafe construction site practices and conditions, and then try to correct them.

Background: Hypertensive disorders in pregnancy (HDP) are associated with coagulation abnormalities. However, results of standard coagulation tests in patients with HDP have been inconsistent. Aim: The aim of this study was to determine mean clotting time (CT) in subjects with HDP attending antenatal clinic at Murtala Muhammad specialist Hospital Kano, Nigeria and to assess CT as a possible predictor of HDP. Materials and Methods: Eighty-four HDP subjects and equal number of normotensive pregnant women were recruited for the study. Blood pressure was measured according to standard protocol. Urinalysis was performed using urine test strips (Medi-Test Combi 9®). Whole-blood CT was determined using capillary tube method. Hypertensive disorders in pregnancy were defined according to the report of National high blood pressure education program working group on high blood pressure in pregnancy. Data were analyzed using IBM SPSS version 23.0. Chi-square test of association and independent t test were used to determine association and difference between categorical and quantitative variables respectively. Pearson’s correlation was used to determine relationship between quantitative variables.

Background: Being an important physiological and clinical tool in assessing respiratory conditions, it is common knowledge that Peak expiratory flow rate (PEFR) may be affected by some factors affecting the normal function of the respiratory system. Such factors include the body constitution such as height, built, sex, age etc.; The trunk-leg ratio (TLR) was used in apparently normal young adults. A better understanding of the association between Trunk-leg ratio and PEFR may identify those with elevated risk of respiratory diseases. Methods: The study was an analytical cross-sectional design, involving 83 Level 200 MBBS/BDS students of Bayero University, Kano. There were a total of 39 males and 44 females.  A peak flow meter and a measuring tape to scale were used to measure the PEFR, trunk length and leg length respectively. A questionnaire was used to determine any history of cardio-respiratory disease A consent of the participants and ethical approval was obtained before the commencement of the study. Results: The males had higher PEFR value (491.79±67.19L/min) while the females had a lower PEFR of 366.82±43.28L/min and the difference was statistically significant. The males had higher values of trunk length, leg length and TLR and there was no significant different between that male and female trunk length ratio. There was A significant correlation between PEFR and leg length indicating that the longer the leg length, the higher the PEFR. Conclusion and Recommendation: Significant correlation was found between the TLR, which is an anthropometric parameter and the PEFR which is an important diagnostic tool in determination of some types of respiratory diseases. This relationship signifies that the taller the person, irrespective of the trunk length, the higher the PEFR. It is recommended that further studies should be explored involving other anthropometric parameters like trunk-leg volume in future studies.