Ethylene will be a major problem in postharvest quality of fresh fruit such as Physalis peruviana L. that belongs to an important medicinal plant. This data article describes the alteration of fruit quality of P. peruviana L. during 21 days of postharvest storage as an effect of ethylene inhibitor, 1-Methylcyclopropene (1-MCP), at different concentration and duration of application. Nutritional parameters and fruit shelf life from 1-MCP treated fruit with three level concentrations (0.5, 1.0, and 2.0 μL L −1 ) and three level of durations application (6, 12 and 24 hours) were analyzed.