Bactibilia was found in 12 samples and Escherichia coli and Klebsiella sp were most often identified in patients with benign diseases, as well as Streptococcus sp and Klebsiella sp in cancer patients. There was a trend of higher postoperative infectious complication incidence in patients with bactibilia.
Objective: Examining the effects of simvastatin on skeletal muscles in an experimental model of abdominal sepsis in rats through the biodistribution of 99mTc-sestamibi. Methods: Wistar rats were randomly assigned to 2 groups: with abdominal sepsis (n = 12) and without sepsis (n = 12). Six animals with sepsis and 6 controls were injected with a daily dose of 5 mg/kg/day of simvastatin by gavage for 3 days before induction of peritonitis and 4 hours before surgical procedure. The others received 1ml of 0.9% saline solution orally. The animals were anesthetized with 20mg/kg of xylazine and 50mg/kg of ketamine i.p. Cecal ligation and puncture were performed by laparotomy. The rats were under observation for 24 hours and their survival time was recorded. The animals were re-anesthetized and 0.1 ml of 99mTc-sestamibi was administered by i.v. 30 minutes later,the thigh muscle was biopsied for percentage of radioactivity per gram of tissue (ATI%/g) determination, measured by the automatic gamma counter Wizard Counter, PerkinElmer,Finland. Results: ATI%/g of Tc99m-sestamibi was higher in muscle samples of groups treated with simvastatin sepsis ((1.820.21), compared with saline-treated (1.070.19) and control groups (1.180.31;1.260.24); this is a statistically significant difference (p<0.001). Conclusion: The data resulting from this study allows for concluding that the pre-treatment with simvastatin contributed to a biodistribution increase of 99mTc-sestamibi into the skeletal muscle in the abdominal sepsis model in rats.
Introdução: Existem duas classificações que estratificam os casos de dengue pelo quadro clínico laboratorial: a classificação proposta nos anos 50 e a revisada pela Organização Mundial de Saúde, adotada em janeiro de 2014 no Brasil. Compará-las quanto à capacidade de identificar a gravidade do caso representa nosso objetivo. Métodos: Estudo observacional e transversal com análise e comparação dos casos de dengue de 2011 a 2013 de um hospital terciário de referência da cidade de Natal/RN, de acordo com a classificação antiga e a classificação revisada. As correspondências adotadas foram: Dengue Clássica e Febre Hemorrágica da Dengue (DHF) grau I com Dengue; DHF grau II com Dengue com sinais de alarme; DHF grau III e IV com Dengue grave. Resultados: 2.318 fichas foram analisadas, com a população predominantemente adulta, média de idade 30,32 anos ± 17,89, sendo 39% do sexo masculino, 61% do sexo feminino. A partir das correlações designadas, 428 casos foram concordantes, 699 discordantes e 1191 “sem classificação” (casos cujos dados dos prontuários não possibilitaram sua classificação). Conclusões: As duas classificações foram equivalentes no manejo clínico quando os casos de dengue foram graves. A classificação antiga evita a superestimação de casos leves e moderados por utilizar mais aspectos clínicos e laboratoriais que a classificação revisada. Sangramento de mucosa, dor abdominal e vômitos não representaram sinais que evoluíram para gravidade, demonstrando como a utilização dos sinais de alarme de maneira imprecisa pode superestimar os dados.
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