Background. Equipment and hospital surfaces constitute a microbial reservoir that can contaminate hospital users and thus create an infectious risk. The aim of this work, which was carried out for the first time at a hospital in Meknes (regional hospital in the center of Morocco), is to evaluate the microbiological quality of surfaces and equipment in three potential risk areas (burn unit, operating room, and sterilization service). Methods. This study was carried out over a period of 4 months (February–May 2017). A total of 60 samples were taken by swabbing according to the standard (ISO/DIS 14698-1 (2004)) in an environment of dry area and equipment after biocleaning. Isolation and identification were performed according to conventional bacteriological methods and by microscopic observation for fungi. Results. The study showed that 40% of surface samples were contaminated after biocleaning. The burn unit recorded a percentage of 70% contamination (p value <0.001), 13% for the sterilization service, and 7% for the operating room. 89% of the isolates were identified as Gram-positive bacteria against 11% for fungi (p value <0.001). Bacterial identification showed coagulase-negative staphylococci (32%), Bacillus spp. (16%), Corynebacterium (8%), and oxidase-negative Gram-positive bacillus (40%) while fungal identification showed Aspergillus niger (n = 2) and Aspergillus nidulans (n = 1). Conclusion. To control the infectious risk related to equipment and hospital surfaces, it would be necessary to evaluate the disinfection protocol applied in these units.

Background: Self-medication is a significant public health problem that negatively affects human health. Many Moroccans have turned to this practice as a form of prevention or treatment for the newly emerged coronavirus disease 2019 (COVID-19) worldwide. Objectives: This study is the first research conducted in Morocco in the context of this pandemic, aiming to explore the prevalence, sources of information, causes, and risk factors of self-medication during the pandemic period. Methods: A cross-sectional survey using a self-administered questionnaire was conducted in the city of Meknes (North Central of Morocco) from March 2022 to June 2022 to investigate the level of self-medication practices before and during the COVID-19 pandemic. Results: The survey included 400 respondents from the general population (mean age = 34.97 ± 15.8 years). The self-medication rate was obtained as 291 (72.75%). There was a statistically significant decrease in the number of respondents practicing self-medication during COVID-19 compared to the pre-pandemic period. Most medications used for self-medication to prevent or treat COVID-19 were supplements such as vitamin C (81.10%) and zinc (74.91%), followed by acetaminophen (72.51%) and herbal products (69.41%). In the bivariate logistic regression model, age, gender, education level, self-reported health, sector of activity, and medical insurance were analyzed. Multivariate analyses showed that the youngest age group (≤ 30 years) (odds ratio (OR) = 1.59; 95% confidence interval (CI): 0.96 - 2.78), university education (OR = 1.47; 95% CI: 0.87 - 2.99), and better self-reported health (OR = 2.83; 95% CI: 1.43 - 3.71) were independently associated with self-medication. Conclusions: Self-medication was a serious health concern in Morocco during the COVID-19 pandemic. This study will be of great interest to the authorities in order to develop new pandemic management strategies, particularly self-medication awareness programs.

This study aimed to evaluate the bactericidal activity of common disinfectants used for surfaces and medical devices. Sodium hypochlorite (D1), disinfectant (D2) composed of N-(3-aminopropyl)-N-dodecylpropane-1,3-diamine, chloride de didecyldimethylammonium, and disinfectant (D3) composed of Didecyldimethylammonium chloride and Polyhexamethylene biguanide hydrochloride, were tested against 15 strains isolated from the hospital environment and four reference bacteria. The microdilution method was performed to assess antimicrobial activity. The susceptibility was evaluated by comparing the minimum inhibitory dilution with the dilution of disinfectant recommended by the manufacture. D1 and D2 were active against Staphylococcus epidermidis, Staphylococcus saprophyticus, Enterobacter cloacae, Escherichia coli, Pseudomonas fluorescens, Methicillin-resistant Staphylococcus aureus, Bacillus spp, Corynebacterium spp, Gram-positive bacillus, Escherichia coli ATCC 25922, Bacillus subtilis ATCC 3366, and Pseudomonas aeruginosa ATCC 27853 strains but not active against Micrococcus spp, and Staphylococcus aureus ATCC 29213. D3 was ineffective against Micrococcus spp, Bacillus Gram Positive, Staphylococcus epidermidis, and Escherichia coli ATCC 25922. Therefore, D1 and D2 can eliminate most pathogenic bacteria in hospitals, in comparison to D3. It is necessary to monitor the antibacterial activity of disinfectants against reference strains but also against those usually present on surfaces. The obtained results could have promising applications in controlling the emergence of nosocomial infections.