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Introduction of LTE-Advanced network brings a series of new techniques as well as an improvement of the existing ones, which contributes to better performance in relation to LTE network. Enhanced MIMO represents one of LTE-Advanced network's most significant techniques which enable considerably better performance. Spectral efficiency and throughput are important system performance indicators. The paper aims to estimate LTE-Advanced network performance by applying an enhanced MIMO. The results verify consistency with given the analytical values, as well as which system parameter has the greatest influence on the achieved results. When enhanced MIMO is applied, several performance testing scenarios have been created depending on the parameter which was analysed for the given scenario, namely: LTE-Advanced channel scenario, antenna configuration, number of HARQ retransmissions and the type of subframe mode.