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The cover depicts two cesium ions (orange) bound inside a molecule that belongs to the calixarene-crown ethers family. These calixarenes are capable of selectively separating more than 99.9975% of the cesium ions from million-fold-higher concentrations of other ions. By studying how such molecules function as extractants, scientists have developed a process * employing a derivative of the cover molecule that is the basis of the Salt Waste Processing Facility being built at the Savannah River Site to remove trace amounts of cesium and other radionuclides from waste left over from reprocessing spent fuel.The graphic is based on an experimentally determined structure † and shows nitrogen atoms in blue, oxygen atoms in red, and carbon ions in gray. The hydrogen atoms bound to each carbon are not shown.

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