Loa loa, a benign filarial nematode eye worm, is endemic in tropical rain forest areas of Africa. It is, especially, common in Cameroon, the Republic of the Congo, the Democratic Republic of the Congo, the Central African Republic, Gabon, Equatorial Guinea, and Nigeria. Travelers and migrants are more commonly found to be infected in India. In the past 100 years, very few cases have been reported in India. In our case, a 9.5 cm-long female eye worm L. loa was recovered from the infraorbital area of a 22-year-old young Indian lady. She presented with a swelling in the right infraorbital area over the face. A history of similar swelling in zygomatic region was noted on the same side 2 months back which disappeared of its own. After ophthalmological opinion and with routine pre-operative evaluation, she was planned for excision under local anesthesia. During procedure, a mobile structure was found suggestive of a live worm. It was further identified as a female species of L. loa macrofilaria on microbilogical examination. The patient was advised oral diethylcarbamazine for 14 days. Post-operative follow-up for 2 years was uneventful.

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Chondroid syringomas are rare, benign adnexal tumor of the skin arising from the eccrine and apocrine sweat gland with tumor differentiation in the epithelial and mesenchymal tissues. In 1859, Billroth first described chondroid syringomas as a mixed tumor of the skin due to its resemblance to the benign mixed tumor arising from salivary gland. [1,2] They most commonly occur in the head and neck, although they may be also found in the limbs, trunk, axilla, genitalia. The reported incidence is <0.01% of all primary skin tumors. An 80-year-old male patient presented to the surgery clinic with a chief complaint of painless, slow-growing swelling on his right mandible, which gradually developed over the period of 20-25yrs. A single, mobile, firm, nontender, nodular surface with subcutaneous plane mass was located on his mandible, which was 6.5cm in diameter. The mass was surgically excised and sent for the histopathological evaluation. The results of biopsy confirmed the diagnosis of chondroid syringoma and showed no evidence of malignancy. In this article, we present a case of giant chondroid syringoma over right mandible in the light of literature review.