No abstract

This study evaluated the effects of L-arginine supplementation on blood parameters, kidney and liver function, immunoglobulins and noninflammatory infiltrates in the small intestines of rats subjected to chemotherapy with 5-fluorouracil (5-FU). Thirty-two Wistar rats were randomly distributed into 4 groups (8 rats/group): an untreated control group, and test groups receiving one dose of 5-FU (G group), one dose of 5-FU and 295 mg L-arginine/day (G group) or one dose of 5-FU and 458 mg L-arginine/day (G group). Neutrophil count, platelet count, serum IgA, and fibrinogen levels in G and G remained within normal limits after chemotherapy. In addition, in G the inflammatory bowel infiltrates improved in 57% of the rats, which showed mild inflammation. The results suggest that daily supplementation with 295 or 458 mg L-arginine attenuates the side effects of 5-FU, including thrombocytopenia and neutropenia, and modulates IgA production. Supplementation with 458 mg of L-arginine/day can also reduce mucositis levels in the small intestine after 5-FU chemotherapy.

No abstract

The objective of this study was to analyze the food intake and nutritional status of women with breast cancer undergoing chemotherapy. The sample consisted of 14 women, over 19 years old, survivors of breast cancer undergoing chemotherapy treatment at the Prudentino Center of Oncology, in the city of Presidente Prudente, SP. Of these, 64.3% were overweight; 71.43% had deficient intake of vitamin A, vitamin E (78.57%) and 71% had inadequate fiber intake. Consumption of 24 ± 9.6 kcal / kg / P and 0.7 ± 0.4 g / kg of protein was observed. It is concluded that food intake is below adequate and overweight is still prevalent in this group of women. It is extremely important to develop strategies for dietary reeducation, emphasizing the importance of healthy and balanced diet for the prevention and treatment of diseases, including breast cancer, aiming at improving nutritional status, maintaining healthy weight, thus contributing to a good prognosis.

This study evaluated the effect of probiotic proenzyme ®, added to the mineral mixture in a weight gain of cattle in extensive grazing system. We used 40 animals, Nelore bulls (Bos indicus) aged approximately 12 months, randomly divided into 2 groups (20 animals / group): control group (CG) received only mineral mixture and probiotic group (GP) with added probiotic. Calves were weighed on days 0 and 30 from 30 to 90 days and 00 to 90 days. The results showed a significant increase in weight gain in animals only GP in the first 30 days