Prediction of the development and susceptibility to acute mountain sickness (AMS) by monitoring oxygen saturation (SpO2)-literature review.

High-altitude pulmonary edema (HAPE) is a life-threatening form of non-cardiogenic pulmonary edema, that develops within the first 2-5 days in rapidly ascending individuals at altitudes above 2,500-3,000 m. The clinical features are cyanosis, tachypnoea, tachycardia and elevated body temperature generally not exceeding 38.5°C. It is often severe and potentially fatal manifestation of acute mountain sickness (AMS). The aim of this study was to assess the methods of prevention and treatment of high altitude pulmonary edema (HAPE). Our study material consisted of publications, which were found in PubMed, ResearchGate and Google Scholar databases. The first step was to find proper publications from the last 30 years .The second step was to carry out an overview of the found publications. Gradual ascent and staged ascent are the most effective methods of prevention of HAPE Pharmacologic prophylaxis with nifedipine should only be considered for individuals with a history of HAPE. Before initiating treatment of HAPE differential diagnosis should be done. Descent should be initiated and oxygen therapy should be started when HAPE is suspected or diagnosed. If these methods are unavailable, nifedipine or Gamow bag can be used.

High altitude cerebral edema (HACE) is often a severe and potentially fatal manifestation of acute mountain sickness (AMS). It usually develops within the first 2 in individuals rapidly ascending at altitudes above 4000 m. The main cause of HACE is hypoxia, because of reduced oxygen level at high altitude. The aim of this study was to assess the methods of prevention and treatment of high altitude cerebral edema (HACE). Our study material consisted of publications, which were found in PubMed, ResearchGate and Google Scholar databases. The first step was to find proper publications from the last 30 years. The second step was to carry out an overview of the found publications. Methods of prevention of acute mountain sickness are highly effective in high altitude cerebral edema prevention. Many studies established the role of gradual ascent and staged ascent as well as administration of acetazolamide and dexamethasone in AMS prevention, and therefore in HACE prevention. Methods of treatments of acute mountain sickness are highly effective in high altitude cerebral edema treatment. Several researches proved the role of descent, administration of acetazolamide and dexamethasone, oxygen therapy as well as use of portable hyperbaric chamber in AMS treatment, and therefore in HACE treatment. However HACE treatment requires greater descent and larger doses of dexamethasone. Also duration of recovery is longer.

Introduction:One of the most common causes of bacterial infections in the world is Helicobacter pylori. It has developed mechanisms that allow it to survive in the acidic pH of the stomach. The bacterium contributes to the incidence of gastric ulcer and duodenal ulcer. Infected is about 50% of the world population, while in Africa the proportion is as high as 80%. Despite this there are still number of African guidelines for infection prevention and eradication of the bacterium. Most infections concerns children, adolescents and the elderly. Data on the diagnosis and treatment of patients in Kenya are inconsistent.[1] Doctors are based on international recommendations. No general insurance and a low level of affluence prevent diagnosis of patients at the level of developed countries. Access to endoscopy, and cultures have only wealthy people in big cities.Purpose: Examine the percentage of Helicobacter pylori infection among the people of Kenya, the analysis of the causes of its high value, comparing the diagnosis and treatment with European standards. Material and methodsAnalysis of causes of hospitalization in 227 hospital patients in Kenya. The majority of them has made winning the test of H. pylori antigen in stool. Analysis of the results of research carried out in 2010Subdepartment Medical Microbiology, Jomo Kenyatta University of Agriculture and Technology in Nairobi, Kenya, where the diagnostic methods was rapid urease test and histological tests. 13 ConclusionsThe proportion of patients infected with H. pylori in Chuka is 51.9%. Cause of inflammation of the stomach in almost 1/3 of hospitalized patients may be awareness of hygiene and drinking water unsuitable for consumption. Standards of treatment of patients infected with H. pylori do not differ from European guidelines.Purpose: Examine the percentage of Helicobacter pylori infection among the people of Kenya, the analysis of the causes of its high value and a reference to the results of research carried out on Jomo Kenyatta University of Agriculture and Technology in Nairobi, Kenya. Comparison of diagnosis and treatment with European standards.

Acute mountain sickness (AMS) is an ilness, that occurs in non-acclimatized individuals after rapid ascent to high altitude, typically above 2,500 metres (8,000 ft). The main causes of the AMS are: reduced air pressure and lower oxygen levels at high altitudes. The early symptoms of AMS are non-specific such as: headache, anorexia, nausea, vomiting, fatigue, dizziness, and sleep disturbance, but not all need to be present at one time. It is very important to recognise the early symptoms of AMS and to start the treatment, because untreated AMS can progress to the life‐threatening: high altitude cerebral edema (HACE) and high altitude pulmonary edema (HAPE). Treatment of AMS consists of stabilization of the patient conditon, descent to lower altitude, oxygen therapy and administering acetazolamide and dexamethasone. The aim of this study was to evaluate the significance of the proper acclimatization, use of the acetazolamide and dexamethasone in prevention of acute mountain sickness (AMS).Proper acclimatization, use of the acetazolamide and dexamethasone are highly effective  in prevention of occurrence and reducing the symptoms of acute mountain sickness (AMS). Pharmacological prophylaxis is not necessary in low-risk situations but should be considered in addition to gradual ascent for use in moderate- to high-risk situations  Acetazolamide should be strongly considered in climbers and travelers at moderate or high risk of AMS with ascent to high altitude. Dexamethasone can be used as an alternative in individuals with a history of intolerance of or allergic reaction to acetazolamide. In rare circumstances (eg, military or rescue teams that must ascend rapidly to and perform physical work at >3500 m), consideration can be given to concurrent use of acetazolamide and dexamethasone.