The purpose of the present longitudinal study was to examine the role of negative work-home interference (WHI) in the classical stressor-strain sequence. First, the predominant time-lagged path between WHI and job stressors was investigated. Furthermore, the direct and indirect (mediating) process of WHI, job stressors, and employee health was examined. The sample consisted of 383 health care employees. Results showed evidence for predominant time-lagged paths from Time 1 job stressors to Time 2 WHI and not the other way around. In addition, it appeared that WHI played a partial mediating role between all 3 types of job stressors on the one hand and exhaustion on the other.

Occupational health researchers utilizing the ERI scales can feel confident that self-reported changes are more likely to be due to factors other than structural change of the ERI scales over time, which has important implications for evaluating job stress and health interventions.

Organozinc radicals, [RZn-t-BuDABl *, which are considered to be key intermediates in the regioselective alkylation reactions of R2Zn compounds with 1,4-di-tert-butyl-l,4-diaza-1,3-butadiene (t-BuDAB), have been prepared via independent routes in good yield either from the reaction of K(t-BuDAB) with RZnCl or by the thermal conversion of stable RzZn-t-BuDAB complexes (R = Me, CH2SiMe3). In solution the [RZn-t-BuDAB]' radicals are in equilibrium with their C-C coupled dimers, which were isolated as solids. A preliminary X-ray diffraction study of one such dimer, 6a, shows the stereoselective coupling of two Me&iCHzZn-t-BuDAB moieties by a C-C bond. The [RZn-t-BuDABI. radicals are reactive toward alkyl halides, like allyl and benzyl bromide, as well as a-and ,&substituted halo esters, producing C-alkylated products in good yield. The reactions with the halo esters give, after a subsequent ring closure reaction, heterocyclic products, Le. B-lactams (with good to excellent diastereoselectivity, de 60-90 % ) and 2-pyrrolidinones.

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