Introduction: Childbirth is often delayed in the contemporary world in view of advancing profession and social reasons. This has lead to increasing infertility. And this also has brought in many studies on age and ovarian reserves even in India. However the northeastern part of India is demographically and geographically different from the rest of India and similar to only a small part of the world population. This study was conducted to find if the above mention factors has any role in the relation of age on ovarian reserve and also with the ABO blood grouping. Material and methods: It was an observational clinical study with a duration of 3 years on patients with infertility. Descriptive and inferential statistical analysis was carried out in the present study. Result: 80% of the study population, irrespective of the age group and blood group has basal FSH < 10mIU/ml. However correlation statistics of age with bFSH shows age (in years) of 35.02±3.13 with bFSH >10mIU/ml and have p value of 0.020. Blood group O shows FSH > 10mIU/ml and blood group A,B,AB does not manifest any relation with FSH. Conclusion: Age has directly related with ovarian reserve represented by basal FSH, and blood group O too has direct correlation with impaired ovarian reserve.

BACKGROUND Obesity is known to be associated with altered thyroid function, increased risk of cardiovascular diseases, diabetes, insulin resistance and metabolic disorders. Thyroid hormones affect body weight through modification of basal metabolic rate. The study aims to assess the BMI and correlate with TSH, f T3, f T4, body fat % and visceral fat level in healthy euthyroid individuals to see if any association between obesity and thyroid status exists. MATERIALS AND METHODS This study was conducted on 92 healthy volunteers amongst the staffs of Jawaharlal Nehru Institute of Medical Sciences (JNIMS), Imphal, Manipur. Anthropometric measurements were done and Body Mass Index (BMI) was calculated. Thyroid Stimulating Hormone (TSH), f T3 and f T4 levels were measured by using chemiluminescent immunoassay and subjects with TSH value between 0.3-3.6 mIU/L were taken for the study. Body fat % and visceral fat level were measured by Bioelectrical Impedance (BI) method by using OMRON-HBF-212 (Body Composition Monitor). Data was analysed using SPSS version 22. The association between variables was determined using ANOVA. RESULTS The study showed significant association of TSH (p= 0.025), body fat % (p= 0.000) and visceral fat level (p= 0.000) with BMI. There was no statistically significant association between body fat % and TSH, f T3, f T4. There was significant association between visceral fat level and f T3. CONCLUSION Serum TSH level increases with increase in fat content of the body, even if the upper limit of TSH is within normal limits. This increased level of body fat % and visceral fat level in obese euthyroid individuals may lead to increased risk for development of obesity related common health problems, thus arising the need to keep the body weight, body fat % and visceral fat level at an acceptable level.

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