Background: The World Health Organization describes polypharmacy as a safe and efficient treatment that complies with evidence-based medicine and uses at least five different medications. Aims and Objectives: The aim of our study was to investigate the impact of polypharmacy in older patients with type 2 diabetes mellitus (T2DM) in rural population in South India. Materials and Methods: The study comprised a total of 100 patients, who were referred to the Government General Hospital, Nizamabad, between January 2020 and March 2022. The records of 50 randomly chosen non-diabetic patients who visited our hospital for other ailments were compared to those of the 50 T2DM patients. Results: In this study, a total of 100 patients were enrolled, out of which 62 were male (62%) and 38 were female (38%). The duration of diabetes was noted to be 0–5 years in 28 patients, 6–10 years in52 patients and >10 years in 20 patients. In our study, we observed that more than five drugs were prescribed to 45 patients in the case group and only ten patients in the control group. Conclusion: Our study shows that older adults with diabetes have a high prevalence of polypharmacy and that this condition may have a significant impact on a number of health-related outcomes. Each patient should receive a customized course of treatment with the right number of medications for their particular ailment. The danger of side effects increases with the number of medications.
Background: Pancreatitis is described as any inflammation that manifests in acute or chronic forms in the pancreas. Acute pancreatitis (AP) is a quick attack that results in pancreatic inflammation and affects the peripancreatic tissue and surrounding organ. Aims and Objectives: This study aims to evaluate lipid profile tests in AP patients. Materials and Methods: The present study was conducted in the Department of General Surgery, Government Medical College, Nizamabad, India, prospectively from July 2019 to May 2022. In our study, we enrolled 100 patients between the age of 20 and 60 and divided them into two groups by random selection. We chose 50 consecutive cases of pancreatitis for the study group and 50 other hospitalized patients for the control group. Results: Mean age of the case group and control group was found to be 39.17±7.42 and 41.92±9.1, respectively. We observed that the peak incidence of pancreatitis occurred between the ages of 40 and 70, with a male predominance in all age categories. When compared to control, low-density lipoprotein cholesterol (P=0.715), total cholesterol (P=0.3124), high-density lipoprotein cholesterol (HDL-C) (0.164), non-HDL-C (0.2436), and triglyceride (P=0.1266) of the study group were found to be statistically non-significant. Conclusion: It is determined that serum lipid profile and pancreatitis are frequently linked. To reduce the risk of developing this disease, prevent its underlying complications, and manage the possibility of subsequent recurrences, patients with the aforementioned risk factors should be assessed for any changes in their serum lipid profile. If such an alteration is discovered, they should be treated with antilipidemic medications, dietary modification, lifestyle change, and physical activity.
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