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Amino silane magnetic nanocomposite decorated on graphene oxide (GO-Fe3O4-APTES) was successfully prepared by organic transformation reaction followed by co-precipitation method. The nanocomposite was characterised by using FT-IR, XRD, FE-SEM, TEM, EDS mapping, VSM, Raman spectroscopy, BET surface area analyzer, Zeta potential and UV-visible spectrophotometer. From TEM results we observed that 8 nm sized particles successfully modified on GO surface. The surface area of GO-Fe3O4-APTES was 57.9 m2 g−1. The magnetic Saturation value of GO-Fe3O4-APTES was 30.6 emu g−1 and the S-like magnetization of all the samples shows super paramagnetic in nature. Due to magnetic nature adsorbent, it could be easily separated from aqueous solution. GO-Fe3O4-APTES material was highly selective for Chromium (VI) removal from aqueous solution. About 91% of Chromium (VI) was removed at pH 3, 160 rpm of shaking speed, 0.3 g l−1 of adsorbent dose and 10 h of contact time. The adsorption process of Chromium (VI) on GO-Fe3O4-APTES follows Pseudo-second-order kinetic and Langmuir isotherm model because of high coefficient of determination value (R2 = 0.99). The maximum adsorption capacity (q m ) of GO-Fe3O4- APTES was observed at 60.53 mg g−1. The synthesized material was desorbed with 0.5 M NaOH and recycled up to five cycles. After five cycles, the removal efficiency of Chromium (VI) possesses high efficacy towards GO-Fe3O4-APTES. Mechanistically, adsorption of Chromium (VI) follows strong electrostatic attraction between adsorbate and adsorbent. GO-Fe3O4-APTES has potential adsorbent for the adsorption of Chromium (VI) in waste water treatment. Furthermore, the GO-Fe3O4-APTES were tested for antibacterial properties against gram negative (Escherichia coli) and gram positive (Bacillus subtilis) bacterial strain. The synthesized material responds positively towards antibacterial activity.

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The hearing organ of Drosophila is present within the second segment of antennae. The hearing organ of Drosophila (Johnston's organ [JO]) shares much structural, developmental, and functional similarity with the vertebrate hearing organ (Organ of Corti). JO is evolving as a potential model system to examine the hearing‐associated defects in vertebrates. In the vertebrates, aminoglycosides like gentamicin, kanamycin, and neomycin have been known to cause defects in the hearing organ. However, a complete mechanism of toxicity is not known. Taking the evolutionary conservation into account the current study aims to test various concentrations of aminoglycoside on the model organism, Drosophila melanogaster. The current study uses the oral route to check the toxicity of various aminoglycosides at different concentrations (50, 100, 150, 200, and 250 μg ml−1). In Drosophila, many foreign particles enter the body through the gut via food. The aminoglycoside treated third instar larvae show defective crawling and sound avoidance behavior. The adult flies release lower amounts of acetylcholine esterase and higher amounts of reactive oxygen species than control untreated animals, accompanied by defective climbing and aggressive behavior. All these behavioral defects are further confirmed by the altered expression level of hearing genes such as nompC, inactive, nanchung, pyrexia. All the behavioral and genetic defects are reported as a readout of aminoglycoside toxicity.