Peripheral giant cell granuloma (PGCG) which is also called as Giant cell Epulis is one of the most common reactive hyperplastic lesions of the oral cavity. There are various etiologies relating PGCG which include local irritation, trauma, tooth extraction, irregular restorations, plaque, calculus, chronic infection & impacted food. One important other etiology of this benign tumor is its origin from periosteum or periodontal membrane. Excision of the lesion completely along with extraction of involved tooth is the option of treatment to prevent recurrence of the lesion in some cases. This case report describes the recurrence of the Peripheral giant cell granuloma even after complete excision in 3 months.Management of recurrent Peripheral giant cell granuloma by surgical excision of the lesion was carried out along with extraction of the associated tooth and curettage of the bone walls. Profuse bleeding after tooth extraction was managed by gel-spun. Periodic recalls doesn't show any recurrence until one month.
Background: The gingival recession causes tooth sensitivity, poor esthetics, and tooth mobility in severe cases. Scientific documentation revealed effective root coverage (RC) and increased keratinized tissue heights acquired with the coronally advanced flap (CAF) for multiple recession defects. Objectives: This research evaluates and compares the efficacy of CAF procedures with and without Type I collagen bio-absorbable membrane in guided tissue regeneration (GTR) in the treatment of Miller's Class I and II gingival recession. Materials and Methods: A total of 30 sites from 15 patients were selected for the study after fulfilling the presurgical phase of treatment. The chosen sites were randomly allocated into Group A CAF and Group B (CAF + Resorbable GTR membrane). The clinical variables such as plaque index, gingival index, recession depth (RD), recession width (RW), width of keratinized gingiva (WKG), clinical attachment level (CAL), and surface area of the defect were recorded at the baseline and 6 months postoperatively. Results: Both therapies resulted in a notable gain in RC with a mean of 73.13% and 71.60%, respectively, but it was not statistically significant when compared between the groups. Both the RD and RW were significantly reduced from baseline to 6 months postoperatively. Although there was a gain in WKG and CAL in both experimental sites, no significant difference was observed between both the groups. Conclusion: Although there are several RC procedures, CAF furnishes a foreseeable, straightforward, and appropriate perspective for treating Miller's Class I and II recessions. Integrating this approach with placing a bio-absorbable membrane does not seem to improve the results following surgical treatment of such defects. However, both groups showed the potential advantage of achieving RC.
Aim The purpose of the present research was to assess the treatment effects of various pharmaceutical agents used by hair implant surgeons to induce hair growth in affected patients. Methodology this study, 500 patients we combined the use of antioxidants, iron, calcium, zinc, amino acids, and vitamins E, D, and C with minoxidil and finasteride to control hair loss, reverse miniaturization, and achieve new hair growth within 2-4 months with group I and II having male participants subjected to cyclic regimen and only minoxidil as well finasteride respectively whereas group II and IV had female participants also following cyclic as well as control regimen respectively. The patients were also followed clinically for 2 years and were observed to maintain their improvement. Results In Group I, the average improvement in density with cyclical medicine was 30% at 2 months and 52% at 4 months. The average improvement in caliber was 37% at 2 months and 47% at 4 months. In control Group II, density improved by an average of 2% at 2 months and 3.6% at 4 months. Caliber was unchanged in 44% of the patients.
Background: The success of any periodontal therapy always depends on better visual access and, magnification is an important component which provides good hand eye coordination with a better treatment outcome. The aim of our study is to assess the effectiveness of magnification over conventional method while performing surgical crown lengthening and to evaluate the patient comfort level and pain perception over a period of 3 months. Methods -The study was conducted amongst 20 patients, 10 in each group requiring crown lengthening for restorative purpose and was evaluated ever a period of 3 months. Results - During 3months follow up, significant differences were found between the groups for probing depth with mean difference of 1.22±0.6, position of gingival margin as with mean 2.7±1.15 and biologic width with mean difference 2.8±0.42.Regarding patient comfort and patients pain perception it was found low for microscope group with mean difference of 2±0.67 Conclusion – A good visual access is a primary requisite behind the success of any periodontal therapy and it was concluded from our study that there was significant reduction in probing depth and improvement in biologic width, gingival margin.
Bone Morphogenetic Proteins (BMPs) are multifunctional growth factors and have the unique property of inducing stem and mesenchymal cell differentiation in to osteogenic cells, capable of producing bone. They are categorized under the super family Transforming Growth Factor-β (TGF-β). In the concept of tissue engineering they are the first approved therapeutic proteins to be used in conjunction with a scaffold and a biocompatible fixative device. Thus in this review the mechanism of action of BMPs is described at its cellular and molecular levels along with its potential clinical applications, utilization perspectives and scientific evidence in periodontal regeneration.
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