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Gender equality in research and innovation (R&I) has improved over the past two decades, although not without its ups and downs. The literature has pointed out the obstacles and difficulties in making gender equality effective in R&I while providing a wide range of strategies, methods and tools to achieve it. Responsible Research and Innovation (RRI) is a new approach that has made gender equality one of its six keys, raising a new challenge for gender mainstreaming. The Horizon Europe Framework Program 2021–2027 represents a step forward, with the Gender Equality Plan as a reference tool for mainstreaming gender in R&I organizations. However, there are more comprehensive proposals, such as the European Institute for Gender Equality’s Gender Mainstreaming Platform. This chapter presents the platform’s content and shows its usefulness in helping prepare Gender Equality Plans and promoting the institutional transformation of R&I organizations.